Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.32 |
| ▸ | KCNJ11 | Q14654 | 3/20 | 0.32 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.32 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.32 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.31 |
| ▸ | METAP2 | P50579 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11624493 | 0.88 | KCNJ11 (0.38) | SORT1KCNJ11ABCC9ABCC8KCNJ8 | |
| SCHEMBL11625399 | 0.85 | NLRP3 (0.38) | NLRP3 | |
| SCHEMBL11628632 | 0.80 | NLRP3 (0.45) | KCNJ11NLRP3CXCR2 | |
| SCHEMBL11620774 | 0.76 | NOS3 (0.34) | MEN1KMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL11626905 | 0.74 | KDM4E (0.33) | MEN1KMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL11625276 | 0.73 | NLRP3 (0.37) | NLRP3 | |
| SCHEMBL11625397 | 0.73 | NLRP3 (0.40) | KCNJ11ABCC9ABCC8KCNJ8NLRP3 | |
| SCHEMBL11624010 | 0.71 | NLRP3 (0.38) | NLRP3ALDH1A1SMN1; SMN2 | |
| SCHEMBL11625273 | 0.70 | NLRP3 (0.39) | NLRP3 | |
| SCHEMBL25845405 | 0.69 | NLRP3 (0.51) | NLRP3ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4093742-A | Anti-hypertensive polyhaloisopropyl-substituted arylureas | SCHERING CORPORATION (US) | 1978-06-06 | — | — | US | disclosed |