Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MC4R | P32245 | 1/20 | 0.45 |
| ▸ | SCN4A | P35499 | 1/20 | 0.45 |
| ▸ | MC3R | P41968 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 8/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11619462 | 0.91 | MAPT (0.55) | ALOX15TDP1LMNAMAPTALDH1A1 | |
| SCHEMBL11636291 | 0.85 | BCHE (0.40) | ALOX15TSHRCYP2C19HIF1ATDP1 | |
| SCHEMBL4338457 | 0.81 | CYP2C19 (0.54) | ALOX15TSHRCYP2C19HIF1ATDP1 | |
| SCHEMBL11619260 | 0.80 | POLB (0.42) | HIF1ATDP1MAPTALDH1A1MAPK1 | |
| Ammonia Solution, Strong SCHEMBL11142977 | 0.80 | CYP2C19 (0.53) | ALOX15TSHRCYP2C19HIF1ATDP1 | |
| SCHEMBL11618680 | 0.79 | ALDH1A1 (0.46) | ALOX15TDP1LMNAMAPTALDH1A1 | |
| SCHEMBL11621277 | 0.76 | RAB9A (0.50) | ALOX15TDP1LMNAMAPTALDH1A1 | |
| SCHEMBL9279198 | 0.74 | HSD17B10 (0.53) | LMNAMAPTALDH1A1SCN5AGAA | |
| SCHEMBL27877981 | 0.74 | CACNA1C (0.50) | ALOX15TSHRCYP2C19HIF1ATDP1 | |
| SCHEMBL11618173 | 0.73 | TSHR (0.49) | ALOX15TSHRCYP2C19LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4101671-A | ANTIULCEROGENICS | BOEHRINGER INGELHEIM GMBH (DE) | 1978-07-18 | — | — | US | disclosed |
| US-RE29628-E | ANTIULCER, SECRETOLYTICS, ANTITUSSIVE | BOEHRINGER INGELHEIM GMBH (DT) | 1978-05-09 | — | — | US | disclosed |
| US-3950393-A | ANTIULCER, ANTISECRETORY, ANTITUSSIVE AGENTS | BOEHRINGER INGELHEIM GMBH (DT) | 1976-04-13 | — | — | US | disclosed |