Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21799602 | 0.84 | RIPK1 (0.43) | RPS6KB1TAAR1 | |
| SCHEMBL21799494 | 0.71 | TAAR1 (0.40) | TAAR1 | |
| SCHEMBL21799515 | 0.70 | RIPK1 (0.43) | RPS6KB1TAAR1 | |
| SCHEMBL11628422 | 0.67 | TYR (0.36) | — | |
| SCHEMBL11624857 | 0.67 | ALDH1A1 (0.41) | ALDH1A1LMNASMN1; SMN2AURKARPS6KB1 | |
| SCHEMBL21799478 | 0.67 | SLC6A3 (0.52) | RPS6KB1TAAR1 | |
| SCHEMBL7455436 | 0.67 | ADORA2A (0.49) | ALDH1A1LMNASMN1; SMN2AURKARPS6KB1 | |
| SCHEMBL8046163 | 0.66 | ALDH1A1 (0.51) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL20993502 | 0.64 | ALDH1A1 (0.39) | HPGDALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL3667006 | 0.64 | CYP1A2 (0.42) | LMNASMN1; SMN2MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4088771-A | 1-Lower alkyl-4,5-dihydro-5-phenyl-2-lower alkoxy carbonylaminoimidazoles and substituted phenyl derivatives thereof | SYNTEX (U.S.A.) INC. (US) | 1978-05-09 | — | — | US | disclosed |