Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 8/20 | 0.75 |
| ▸ | CA2 | P00918 | 8/20 | 0.75 |
| ▸ | CA9 | Q16790 | 4/20 | 0.68 |
| ▸ | CA12 | O43570 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | CA7 | P43166 | 3/20 | 0.60 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30628487 | 0.81 | CA1 (0.86) | CA1CA2CA9CA12MAPT | |
| SCHEMBL15888499 | 0.81 | CA1 (0.86) | CA1CA2CA9CA12MAPT | |
| SCHEMBL11887649 | 0.80 | CA1 (0.77) | CA1CA2CA9CA12TDP1 | |
| SCHEMBL15888505 | 0.78 | CA2 (0.74) | CA1CA2CA9CA12MAPT | |
| SCHEMBL11624368 | 0.78 | ALDH1A1 (0.53) | CA1CA2CA9CA12MAPT | |
| SCHEMBL11807861 | 0.77 | MEN1 (0.87) | CA1CA2CA9CA12CA7 | |
| SCHEMBL4305965 | 0.77 | CA1 (0.89) | CA1CA2CA9CA12MAPT | |
| SCHEMBL11628147 | 0.77 | ALDH1A1 (0.53) | CA1CA2MAPTTDP1TSHR | |
| SCHEMBL13401865 | 0.76 | CA1 (0.86) | CA1CA2CA9CA12TDP1 | |
| SCHEMBL6046379 | 0.76 | MEN1 (0.90) | CA1CA2CA9CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4066639-A | BENZENE-SULFONYL SEMICARBAZIDES AND PROCESS FOR PREPARING THEM | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-01-03 | — | — | US | disclosed |