Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.76 |
| ▸ | MAPT | P10636 | 2/20 | 0.76 |
| ▸ | HTT | P42858 | 2/20 | 0.76 |
| ▸ | LMNA | P02545 | 2/20 | 0.76 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | VNN1 | O95497 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | NAMPT | P43490 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | MMP13 | P45452 | 1/20 | 0.62 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11626058 | 0.87 | VNN1 (0.67) | ALDH1A1MAPTHTTLMNASORT1 | |
| SCHEMBL1568226 | 0.87 | ALDH1A1 (0.72) | ALDH1A1MAPTHTTLMNAMEN1 | |
| SCHEMBL13483867 | 0.86 | LMNA (1.00) | ALDH1A1MAPTHTTLMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11627866 | 0.86 | VNN1 (0.65) | ALDH1A1MAPTHTTLMNASORT1 | |
| SCHEMBL5783915 | 0.86 | HTT (0.71) | ALDH1A1MAPTHTTLMNAMEN1 | |
| SCHEMBL16286423 | 0.85 | MEN1 (0.65) | ALDH1A1MAPTHTTLMNASORT1 | |
| SCHEMBL14082729 | 0.85 | KDM1A (0.61) | ALDH1A1MAPTHTTLMNASORT1 | |
| SCHEMBL6569317 | 0.84 | LMNA (0.72) | ALDH1A1MAPTHTTLMNAMEN1 | |
| SCHEMBL5257811 | 0.84 | LMNA (0.72) | ALDH1A1MAPTHTTLMNASMN1; SMN2 | |
| SCHEMBL11628816 | 0.84 | NAMPT (0.67) | ALDH1A1HTTLMNASORT1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4069224-A | N-(PYRIDYLALKYL)BENZAMIDES, IMPROVE PRODUCTION OF PROSTAGLANDINS IN MAMMALS | THE UPJOHN COMPANY (US) | 1978-01-17 | — | — | US | claimed |
| US-4069224-A | N-(PYRIDYLALKYL)BENZAMIDES, IMPROVE PRODUCTION OF PROSTAGLANDINS IN MAMMALS | THE UPJOHN COMPANY (US) | 1978-01-17 | — | — | US | disclosed |