Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 3/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.42 |
| ▸ | GSK3B | P49841 | 3/20 | 0.42 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.42 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3118199 | 0.84 | KDM4E (0.45) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL11626453 | 0.82 | ALDH1A1 (0.52) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL11624104 | 0.81 | MAP2 (0.41) | ALDH1A1KDM4EMEN1KMT2AGSK3B | |
| SCHEMBL11735516 | 0.77 | KDM4E (0.52) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL11626370 | 0.76 | PARP1 (0.49) | MAPTMEN1KMT2ACDK1CCNB1 | |
| SCHEMBL11732071 | 0.75 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL15486288 | 0.73 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL2730451 | 0.73 | KDM4E (0.56) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL1384138 | 0.71 | RAB9A (0.55) | ALDH1A1KDM4EHPGDMAPTHSD17B10 | |
| SCHEMBL15332126 | 0.70 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4069230-A | CYCLIZATION OF HYDRAZONE COMPOUND, INTERMEDIATE FOR BENZODIAZEPINES | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1978-01-17 | — | — | US | disclosed |