Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.46 |
| ▸ | IKBKB | O14920 | 3/20 | 0.45 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | PRNP | P04156 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11625359 | 0.88 | RXFP1 (0.47) | ALDH1A1MAPTKDM4EGAARXFP1 | |
| SCHEMBL11624275 | 0.82 | LMNA (0.52) | ALDH1A1MAPTKDM4EGAAKMT2A | |
| SCHEMBL5105534 | 0.77 | LIMK1 (0.60) | ALDH1A1MAPTKDM4EGAARXFP1 | |
| SCHEMBL14615049 | 0.77 | CYP2C9 (0.44) | ALDH1A1MAPTKDM4EGAARXFP1 | |
| SCHEMBL14615044 | 0.74 | ALDH1A1 (0.40) | ALDH1A1MAPTKDM4EGAARXFP1 | |
| SCHEMBL10758156 | 0.74 | CYP2A6 (0.43) | ALDH1A1MAPTKDM4EGAARXFP1 | |
| Hydrochloric Acid SCHEMBL11625551 | 0.72 | CYP2A6 (0.42) | ALDH1A1MAPTKDM4EGAARXFP1 | |
| SCHEMBL16581237 | 0.71 | GABRA1 (0.55) | ALDH1A1MAPTKDM4EGAAIKBKB | |
| SCHEMBL11602025 | 0.71 | MAOB (0.70) | ALDH1A1MAPTKMT2ALMNAMAOA | |
| SCHEMBL14615113 | 0.71 | ALDH1A1 (0.49) | ALDH1A1MAPTKDM4EGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4122034-A | 2-AMINO-3-ARYL-HETEROINDENES | SCHERING CORPORATION (US) | 1978-10-24 | — | — | US | disclosed |