Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GRM8 | O00222 | 1/20 | 0.31 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 2/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.30 |
| ▸ | PDE6D | O43924 | 1/20 | 0.30 |
| ▸ | PDE6A | P16499 | 1/20 | 0.30 |
| ▸ | PDE6G | P18545 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE6B | P35913 | 1/20 | 0.30 |
| ▸ | PDE6C | P51160 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | PDE6H | Q13956 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1937435 | 0.81 | KDM4E (0.37) | ALDH1A1KDM4EPDE2APDE10APDE6D | |
| SCHEMBL1937549 | 0.81 | NPC1 (0.36) | PDE2APDE10APDE6DPDE6APDE6G | |
| SCHEMBL1162406 | 0.81 | CYP1A2 (0.33) | ALDH1A1CYP1A2CYP3A4GRM8GRM7 | |
| SCHEMBL1162305 | 0.79 | CYP1A2 (0.34) | ALDH1A1CYP1A2CYP3A4GRM8GRM7 | |
| SCHEMBL14324084 | 0.79 | ALDH1A1 (0.37) | ALDH1A1CYP1A2CYP3A4KDM4E | |
| SCHEMBL29184356 | 0.77 | MEN1 (0.34) | ALDH1A1CYP1A2CYP3A4GRM8GRM7 | |
| SCHEMBL30284776 | 0.77 | MEN1 (0.34) | ALDH1A1CYP1A2CYP3A4GRM8GRM7 | |
| SCHEMBL2347440 | 0.77 | NPC1 (0.39) | ALDH1A1CYP1A2KDM4E | |
| SCHEMBL1162374 | 0.75 | CYP1A2 (0.37) | ALDH1A1CYP1A2CYP3A4GRM8GRM7 | |
| SCHEMBL1559111 | 0.74 | NPC1 (0.37) | PDE2APDE10APDE6DPDE6APDE6G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2462120-A1 | FUNGICIDAL DIPHENYL-SUBSTITUTED PYRIDAZINES | E. I. du Pont de Nemours and Company (US) | 2012-06-13 | — | — | EP | disclosed |
| US-20120135995-A1 | FUNGICIDAL DIPHENYL-SUBSTITUTED PYRIDAZINES | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2012-05-31 | — | — | US | disclosed |
| WO-2011017261-A1 | FUNGICIDAL DIPHENYL-SUBSTITUTED PYRIDAZINES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-02-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135995-A1 | FUNGICIDAL DIPHENYL-SUBSTITUTED PYRIDAZINES | PNPO, CYP1B1, PRXL2A | ALDH1A1 744/4885CYP1A2 21/4885CYP3A4 120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.