Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 5/20 | 0.71 |
| ▸ | SLC5A2 | P31639 | 5/20 | 0.71 |
| ▸ | MAPT | P10636 | 8/20 | 0.70 |
| ▸ | HPGD | P15428 | 4/20 | 0.70 |
| ▸ | MEN1 | O00255 | 4/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.70 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 6/20 | 0.66 |
| ▸ | HTT | P42858 | 3/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 6/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5036945 | 0.87 | MAPT (0.77) | SLC5A1SLC5A2MAPTHPGDMEN1 | |
| SCHEMBL15040779 | 0.83 | MAPT (0.61) | SLC5A1SLC5A2MAPTHPGDMEN1 | |
| SCHEMBL458222 | 0.83 | SLC5A1 (1.00) | SLC5A1SLC5A2MAPTHPGDMEN1 | |
| SCHEMBL11628971 | 0.82 | SLC5A1 (0.71) | SLC5A1SLC5A2MAPTHPGDMEN1 | |
| SCHEMBL145265 | 0.81 | LMNA (0.78) | SLC5A1SLC5A2MAPTHPGDMEN1 | |
| SCHEMBL24841623 | 0.80 | CYP19A1 (0.70) | SLC5A1SLC5A2MAPTHPGDMEN1 | |
| SCHEMBL3958571 | 0.79 | LMNA (1.00) | MAPTHPGDMEN1KMT2AMAPK1 | |
| SCHEMBL17838423 | 0.79 | LMNA (0.53) | SLC5A1SLC5A2MAPTHPGDMEN1 | |
| SCHEMBL1224101 | 0.78 | SLC5A1 (0.75) | SLC5A1SLC5A2MAPTHPGDMEN1 | |
| SCHEMBL16322177 | 0.76 | LMNA (0.77) | SLC5A1SLC5A2MAPTHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4117149-A | 4-OXO-4H-BENZOPYRANS AS ANIMAL GROWTH PROMOTANTS | PFIZER INC. (US) | 1978-09-26 | — | — | US | disclosed |