SCHEMBL5036945

SCHEMBL5036945

O=C(Cc1ccc(O)cc1)c1c(O)cc(O)cc1O

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.77
HPGD P15428 4/20 0.77
MEN1 O00255 4/20 0.77
KMT2A Q03164 4/20 0.77
CYP3A4 P08684 3/20 0.77
MAPK1 P28482 2/20 0.77
PIK3CA P42336 1/20 0.77
GAA P10253 6/20 0.68
LMNA P02545 5/20 0.68
SLC5A1 P13866 5/20 0.68
SLC5A2 P31639 5/20 0.68
ESR1 P03372 2/20 0.68
ALDH1A1 P00352 2/20 0.68
HSD17B10 Q99714 2/20 0.68
CYP19A1 P11511 2/20 0.68
KDM4E B2RXH2 1/20 0.68
SLC16A3 O15427 1/20 0.68
TTR P02766 1/20 0.68
TP53 P04637 1/20 0.68
CYP1A2 P05177 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15040779 0.88 MAPT (0.61) MAPTHPGDMEN1KMT2ACYP3A4
SCHEMBL13991130 0.88 LMNA (0.79) MAPTHPGDMEN1KMT2ACYP3A4
SCHEMBL5622899 0.88 MAPT (0.71) MAPTHPGDMEN1KMT2ACYP3A4
SCHEMBL11627675 0.87 SLC5A1 (0.71) MAPTHPGDMEN1KMT2ACYP3A4
SCHEMBL11628971 0.87 SLC5A1 (0.71) MAPTHPGDMEN1KMT2ACYP3A4
SCHEMBL145265 0.86 LMNA (0.78) MAPTHPGDMEN1KMT2ACYP3A4
SCHEMBL24841623 0.85 CYP19A1 (0.70) MAPTHPGDMEN1KMT2ACYP3A4
SCHEMBL6396380 0.84 MAPT (0.56) MAPTHPGDMEN1KMT2ACYP3A4
SCHEMBL1224101 0.83 SLC5A1 (0.75) MAPTHPGDMEN1KMT2ACYP3A4
Phloretin SCHEMBL38131 0.81 SLC5A1 (1.00) MAPTHPGDMEN1KMT2ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250084049-A1 POLYCATIONIC SALTS OF PHENOLIC COMPOUNDS AND USES THEREOF FIRMENICH INCORPORATED (US) 2025-03-13 US disclosed
WO-2023278394-A1 POLYCATIONIC SALTS OF PHENOLIC COMPOUNDS AND USES THEREOF FIRMENICH INCORPORATED (US) 2023-01-05 WO disclosed
US-9388273-B2 Multifunctional deoxybenzoin-based monomers and resins having reduced flammability UNIVERSITY OF MASSACHUSETTS (US) 2016-07-12 US disclosed
US-9388273-B2 Multifunctional deoxybenzoin-based monomers and resins having reduced flammability UNIVERSITY OF MASSACHUSETTS (US) 2016-07-12 US disclosed
US-9388273-B2 Multifunctional deoxybenzoin-based monomers and resins having reduced flammability UNIVERSITY OF MASSACHUSETTS (US) 2016-07-12 US disclosed
US-9388273-B2 Multifunctional deoxybenzoin-based monomers and resins having reduced flammability UNIVERSITY OF MASSACHUSETTS (US) 2016-07-12 US disclosed
WO-2016073947-A1 ANTI-VIRAL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF Kineta, Inc. (US) 2016-05-12 WO disclosed
US-20160122312-A1 ANTI-VIRAL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREOF Kineta, Inc. 2016-05-05 US disclosed
US-20160122312-A1 ANTI-VIRAL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREOF Kineta, Inc. 2016-05-05 US disclosed
WO-2015009812-A2 ANTI-VIRAL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF Kineta, Inc. (US) 2015-01-22 WO disclosed
US-20140357829-A1 MULTIFUNCTIONAL DEOXYBENZOIN-BASED MONOMERS AND RESINS HAVING REDUCED FLAMMABILITY UNIVERSITY OF MASSACHUSETTS 2014-12-04 US disclosed
US-20140357829-A1 MULTIFUNCTIONAL DEOXYBENZOIN-BASED MONOMERS AND RESINS HAVING REDUCED FLAMMABILITY UNIVERSITY OF MASSACHUSETTS 2014-12-04 US disclosed
US-20140357829-A1 MULTIFUNCTIONAL DEOXYBENZOIN-BASED MONOMERS AND RESINS HAVING REDUCED FLAMMABILITY UNIVERSITY OF MASSACHUSETTS 2014-12-04 US disclosed
US-20090062555-A1 Synthesis of Isoflavone BAUSCH & LOMB INCORPORATED 2009-03-05 US disclosed
US-20090062555-A1 Synthesis of Isoflavone BAUSCH & LOMB INCORPORATED 2009-03-05 US disclosed
US-7326797-B2 Manufacture of isoflavones DSM IP ASSETS B.V. (NL) 2008-02-05 US disclosed
EP-1523478-B1 MANUFACTURE OF ISOFLAVONES DSM IP ASSETS BV (NL) 2007-12-12 EP disclosed
US-20050256321-A1 Manufacture of isoflavones DSM IP ASSETS B.V. (NL) 2005-11-17 US disclosed
EP-1523478-A2 MANUFACTURE OF ISOFLAVONES DSM IP Assets B.V. (NL) 2005-04-20 EP disclosed
WO-2004009576-A2 MANUFACTURE OF ISOFLAVONES DSM IP ASSETS B.V. (NL) 2004-01-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090062555-A1 Synthesis of Isoflavone HSD17B7, F3, AKR1C3 MAPT 4338/4885HPGD 767/4885MEN1 1185/4885
US-20250084049-A1 POLYCATIONIC SALTS OF PHENOLIC COMPOUNDS AND USES THEREOF PGC, SLC5A6, PUF60 MAPT 3007/4885HPGD 1526/4885MEN1 2672/4885
US-20160122312-A1 ANTI-VIRAL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREOF MAVS, EIF2AK2, IRF3 MAPT 3846/4885HPGD 3295/4885MEN1 4806/4885
US-20140357829-A1 MULTIFUNCTIONAL DEOXYBENZOIN-BASED MONOMERS AND RESINS HAVING REDUCED FLAMMABILITY FLAD1, MMAB, FLNB MAPT 3054/4885HPGD 391/4885MEN1 4182/4885
US-20050256321-A1 Manufacture of isoflavones HAAO, HAO2, CYP2F1 MAPT 4700/4885HPGD 71/4885MEN1 3253/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.