Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABAT | P80404 | 1/20 | 0.37 |
| ▸ | ERCC1 | P07992 | 2/20 | 0.36 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | MARS1 | P56192 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1821169 | 0.88 | LCK (0.42) | ABATLCKFYNDAOHPGD | |
| SCHEMBL11626031 | 0.77 | ERCC1 (0.55) | ABATERCC1ERCC4KMT2ACA12 | |
| SCHEMBL11630985 | 0.75 | GRIK1 (0.38) | LCKFYNDAOHPGDPOLB | |
| SCHEMBL11630438 | 0.75 | TDP1 (0.51) | HPGDPOLBKMT2ATDP1MAPT | |
| SCHEMBL7391543 | 0.74 | POLB (0.47) | LCKFYNDAOHPGDPOLB | |
| SCHEMBL11623311 | 0.72 | KMT2A (0.35) | KMT2ATDP1MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL6715569 | 0.71 | ALDH1A1 (0.53) | HPGDKMT2AMAPTALDH1A1LMNA | |
| SCHEMBL12181448 | 0.70 | HDAC1 (0.58) | LCKFYNDAOHPGDPOLB | |
| SCHEMBL9329742 | 0.70 | GAA (0.43) | ABATHPGDPOLBKMT2ATDP1 | |
| SCHEMBL11627982 | 0.69 | ERCC1 (0.48) | ABATERCC1ERCC4ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4086423-A | CEPHALOSPORINS, CYCLOADDITION OF GLYCINE DERIVATIVE TO THIAZINE COMPOUND | MERCK & CO., INC. (US) | 1978-04-25 | — | — | US | disclosed |