Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11629474 | 0.91 | LMNA (0.46) | LMNAPOLBALDH1A1KDM4ETSHR | |
| SCHEMBL11621805 | 0.85 | ALDH1A1 (0.43) | LMNAPOLBSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL11812242 | 0.84 | ALDH1A1 (0.39) | LMNAPOLBGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL11626390 | 0.79 | MAPT (0.48) | LMNAGAASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL11624509 | 0.76 | MEN1 (0.49) | LMNASMN1; SMN2ALDH1A1KDM4ETSHR | |
| SCHEMBL11625348 | 0.75 | MEN1 (0.52) | LMNAPOLBGAAALDH1A1KDM4E | |
| SCHEMBL13664124 | 0.75 | LMNA (0.56) | LMNAPOLBGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL10969853 | 0.73 | LMNA (0.68) | LMNAPOLBGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL19249613 | 0.73 | LMNA (0.42) | LMNAPOLBGAAALDH1A1KDM4E | |
| SCHEMBL13664107 | 0.72 | LMNA (0.62) | LMNAPOLBSMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4071562-A | 4,5-Dialkoxy-6 or 7-indanaldehydes | MARION LABORATORIES, INC. (US) | 1978-01-31 | — | — | US | disclosed |
| US-3963723-A | HYPOTENSIVE | MARION LABORATORIES, INC. (US) | 1976-06-15 | — | — | US | disclosed |
| US-3954774-A | HYPOTENSIVE AGENTS | MARION LABORATORIES, INC. (US) | 1976-05-04 | — | — | US | disclosed |