Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11628367 | 0.91 | LMNA (0.49) | LMNAMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL11624509 | 0.86 | MEN1 (0.49) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL11623589 | 0.80 | ALDH1A1 (0.46) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL11621805 | 0.79 | ALDH1A1 (0.43) | LMNAMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL11812242 | 0.78 | ALDH1A1 (0.39) | LMNAMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL834457 | 0.78 | MEN1 (0.50) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL10773535 | 0.76 | LMNA (0.53) | LMNAPOLBALDH1A1KDM4ETSHR | |
| SCHEMBL11629337 | 0.75 | MEN1 (0.56) | LMNAMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL835754 | 0.75 | MEN1 (0.48) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL836902 | 0.75 | MEN1 (0.48) | LMNAMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4071562-A | 4,5-Dialkoxy-6 or 7-indanaldehydes | MARION LABORATORIES, INC. (US) | 1978-01-31 | — | — | US | disclosed |
| US-3963723-A | HYPOTENSIVE | MARION LABORATORIES, INC. (US) | 1976-06-15 | — | — | US | disclosed |
| US-3954774-A | HYPOTENSIVE AGENTS | MARION LABORATORIES, INC. (US) | 1976-05-04 | — | — | US | disclosed |