Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.38 |
| ▸ | PDE4A | P27815 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | GCK | P35557 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | GALR3 | O60755 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11631951 | 0.83 | MAPK1 (0.46) | MAPK1KDM4ERXFP1HPGDPDE3A | |
| SCHEMBL11627508 | 0.74 | PLA2G10 (0.45) | MAPK1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL11629754 | 0.71 | GUSB (0.48) | MAPK1KDM4EHPGDALDH1A1GAA | |
| SCHEMBL11629253 | 0.71 | PTGES (0.44) | MAPK1KDM4EHPGDLMNAGCK | |
| SCHEMBL11629965 | 0.71 | GUCY1B2 (0.48) | MAPK1KDM4EHPGDGCKALDH1A1 | |
| SCHEMBL11625206 | 0.71 | HTT (0.54) | MAPK1KDM4EPDE5ALMNAALDH1A1 | |
| SCHEMBL11628494 | 0.71 | MAPK1 (0.45) | MAPK1KDM4ERXFP1HPGDPDE3A | |
| SCHEMBL23900415 | 0.70 | MAPK1 (0.56) | MAPK1KDM4ERXFP1HPGDPDE3A | |
| SCHEMBL3521755 | 0.70 | RECQL (0.54) | MAPK1KDM4EHPGDGCKALDH1A1 | |
| SCHEMBL11625024 | 0.69 | PDE5A (0.56) | MAPK1KDM4EHPGDPDE5AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4082751-A | ANTIALLERGENS | BRISTOL-MYERS COMPANY (US) | 1978-04-04 | — | — | US | disclosed |