Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.48 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.48 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.48 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.48 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | CHUK | O15111 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11629253 | 0.82 | PTGES (0.44) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1PTGES | |
| SCHEMBL11629754 | 0.82 | GUSB (0.48) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1PTGES | |
| SCHEMBL11625206 | 0.79 | HTT (0.54) | PTGESMAPK1ALDH1A1L3MBTL1PDE10A | |
| SCHEMBL11628494 | 0.79 | MAPK1 (0.45) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1PTGES | |
| SCHEMBL3521755 | 0.78 | RECQL (0.54) | MAPK1CHUKALDH1A1NPC1RAB9A | |
| SCHEMBL31558577 | 0.77 | ALDH1A1 (0.41) | PTGESALDH1A1NPC1PKMRAB9A | |
| SCHEMBL11625024 | 0.77 | PDE5A (0.56) | MAPK1ALDH1A1PDE10AKDM4EHPGD | |
| SCHEMBL11629633 | 0.76 | PDE5A (0.50) | PTGESMAPK1GCK | |
| SCHEMBL11631943 | 0.76 | MAPK1 (0.58) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1PTGES | |
| SCHEMBL11628419 | 0.75 | PDE5A (0.56) | ALDH1A1PDE10AKDM4EHPGDHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4082751-A | ANTIALLERGENS | BRISTOL-MYERS COMPANY (US) | 1978-04-04 | — | — | US | disclosed |