Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | DPYD | Q12882 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.41 |
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GALR3 | O60755 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27658904 | 0.76 | MAPK1 (0.51) | MAPK1DPYDKDM4EHPGDPDE3A | |
| SCHEMBL2027355 | 0.76 | MAPK1 (0.69) | MAPK1DPYDKDM4EHPGDPDE3A | |
| SCHEMBL22866409 | 0.73 | MAPK1 (0.39) | MAPK1KDM4EPDE4ACYP2C19LMNA | |
| SCHEMBL29559852 | 0.73 | MAPK1 (0.39) | MAPK1KDM4EPDE4ACYP2C19LMNA | |
| SCHEMBL14072055 | 0.72 | MAPK1 (0.47) | MAPK1DPYDKDM4EKMT2ANPSR1 | |
| SCHEMBL11629097 | 0.72 | MAPK1 (0.47) | MAPK1DPYDKDM4EHPGDPDE3A | |
| SCHEMBL22866407 | 0.71 | PARP1 (0.39) | MAPK1KDM4ECYP2C19GAAALDH1A1 | |
| SCHEMBL29561211 | 0.71 | PARP1 (0.39) | MAPK1KDM4ECYP2C19GAAALDH1A1 | |
| SCHEMBL11628504 | 0.70 | MAPK1 (0.43) | MAPK1KDM4EHPGDPDE3APDE4A | |
| SCHEMBL4359016 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743456-A1 | COMPOUNDS, PREPARATION METHODS AND USES THEREOF | InventisBio Co., Ltd. (CN) | 2026-05-20 | — | — | EP | disclosed |
| US-20250361223-A1 | AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LTD (CN) | 2025-11-27 | — | — | US | disclosed |
| US-12435062-B2 | Amide compounds and uses thereof | HUTCHISON MEDIPHARMA LIMITED (CN) | 2025-10-07 | — | — | US | disclosed |
| WO-2025016314-A1 | COMPOUNDS, PREPARATION METHODS AND USES THEREOF | InventisBio Co., Ltd. (CN) | 2025-01-23 | — | — | WO | disclosed |
| CN-117777103-A | Amide compound and application thereof | 和记黄埔医药（上海）有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-117720520-A | Amide compound and application thereof | 和记黄埔医药（上海）有限公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-117720519-A | Amide compound and application thereof | 和记黄埔医药（上海）有限公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-115315422-B | Amide compound and application thereof | 和记黄埔医药（上海）有限公司 | 2023-11-07 | — | — | CN | disclosed |
| US-20230174513-A1 | AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2023-06-08 | — | — | US | disclosed |
| US-20230174513-A1 | AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2023-06-08 | — | — | US | disclosed |
| EP-4126844-A1 | AMIDE COMPOUNDS AND USES THEREOF | Hutchison Medipharma Limited (CN) | 2023-02-08 | — | — | EP | disclosed |
| CN-115315422-A | Amide compound and application thereof | 和记黄埔医药（上海）有限公司 | 2022-11-08 | — | — | CN | disclosed |
| WO-2021197276-A1 | Amide compounds and uses thereof | HUTCHISON MEDIPHARMA LIMITED (CN) | 2021-10-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230174513-A1 | AMIDE COMPOUNDS AND USES THEREOF | ASNS, ASS1, NAT1 | MAPK1 2993/4885DPYD 647/4885KDM4E 1449/4885 |
| US-12435062-B2 | Amide compounds and uses thereof | ASNS, ASS1, NAT1 | MAPK1 2993/4885DPYD 647/4885KDM4E 1449/4885 |
| US-20250361223-A1 | AMIDE COMPOUNDS AND USES THEREOF | ASNS, NAT1, AADAC | MAPK1 3036/4885DPYD 708/4885KDM4E 1690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.