Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21846702 | 0.74 | ALDH1A1 (0.37) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7487076 | 0.69 | SMN1; SMN2 (0.37) | — | |
| SCHEMBL1053481 | 0.69 | KMT2A (0.36) | — | |
| SCHEMBL17532417 | 0.68 | ALDH1A1 (0.42) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28116056 | 0.68 | KMT2A (0.34) | — | |
| SCHEMBL28409054 | 0.67 | ALDH1A1 (0.34) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL12308315 | 0.66 | SMN1; SMN2 (0.39) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL13532554 | 0.66 | SMN1; SMN2 (0.39) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3613221 | 0.66 | KMT2A (0.36) | — | |
| SCHEMBL1147306 | 0.65 | SMN1; SMN2 (0.38) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4069377-A | Polymerization of ethylenically unsaturated monomers employing secondary-aliphatic α-substituted azoalkanes | PENNWALT CORPORATION | 1978-01-17 | — | — | US | disclosed |
| US-4025502-A | POLYMERIZATION CATALYSTS, CURING AGENTS | PENNWALT CORPORATION (US) | 1977-05-24 | — | — | US | disclosed |