Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.42 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 2/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | CHUK | O15111 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL82637 | 0.77 | NAPRT (0.67) | PDPK1NAPRTKDM4EALDH1A1MAPT | |
| SCHEMBL9936824 | 0.75 | GAA (0.68) | PDPK1NAPRTKDM4EALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL30935942 | 0.75 | NAPRT (0.64) | PDPK1NAPRTKDM4EALDH1A1MAPT | |
| SCHEMBL564004 | 0.72 | PDPK1 (0.44) | PDPK1NAPRTKDM4EALDH1A1MAPT | |
| SCHEMBL5139889 | 0.71 | CSNK1A1 (0.54) | PDPK1NAPRTKDM4EALDH1A1MAPT | |
| SCHEMBL31120424 | 0.71 | CSNK1A1 (0.54) | PDPK1NAPRTKDM4EALDH1A1MAPT | |
| Formic Acid SCHEMBL30227578 | 0.71 | NAPRT (0.58) | PDPK1NAPRTKDM4EALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL29749317 | 0.69 | CSNK1A1 (0.53) | PDPK1NAPRTKDM4EALDH1A1MAPT | |
| SCHEMBL39118 | 0.69 | ALDH1A1 (0.70) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL4967588 | 0.69 | ALDH1A1 (0.70) | KDM4EALDH1A1MAPTHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4086423-A | CEPHALOSPORINS, CYCLOADDITION OF GLYCINE DERIVATIVE TO THIAZINE COMPOUND | MERCK & CO., INC. (US) | 1978-04-25 | — | — | US | claimed |