Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | LMNA | P02545 | 4/20 | 0.76 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.74 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | MMP13 | P45452 | 1/20 | 0.62 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | NAMPT | P43490 | 1/20 | 0.62 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.62 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24975354 | 0.88 | HTT (0.77) | HTTALDH1A1LMNANPSR1KMT2A | |
| SCHEMBL16286298 | 0.87 | MEN1 (0.81) | HTTALDH1A1LMNANPSR1KMT2A | |
| SCHEMBL11630628 | 0.86 | ALDH1A1 (0.76) | HTTALDH1A1LMNANPSR1KMT2A | |
| SCHEMBL16286312 | 0.86 | ALDH1A1 (0.76) | HTTALDH1A1LMNANPSR1KMT2A | |
| SCHEMBL12334898 | 0.85 | NAMPT (0.80) | HTTALDH1A1LMNANPSR1KMT2A | |
| SCHEMBL29996180 | 0.84 | HTT (0.72) | HTTALDH1A1LMNANPSR1KMT2A | |
| SCHEMBL23063861 | 0.84 | HTT (0.72) | HTTALDH1A1LMNANPSR1KMT2A | |
| SCHEMBL13102334 | 0.83 | MMP13 (0.85) | HTTALDH1A1LMNAKMT2AMAPT | |
| SCHEMBL29437161 | 0.83 | MMP13 (0.85) | HTTALDH1A1LMNAKMT2AMAPT | |
| SCHEMBL10076246 | 0.82 | TRPV1 (0.74) | HTTALDH1A1LMNANPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4069224-A | N-(PYRIDYLALKYL)BENZAMIDES, IMPROVE PRODUCTION OF PROSTAGLANDINS IN MAMMALS | THE UPJOHN COMPANY (US) | 1978-01-17 | — | — | US | disclosed |