Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 7/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
| ▸ | PLAU | P00749 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11625490 | 0.90 | MEN1 (0.35) | POLBMEN1KMT2ANLRP3 | |
| SCHEMBL11629132 | 0.76 | HTR2A (0.43) | POLBGAATSHRALDH1A1HPGD | |
| SCHEMBL11666838 | 0.75 | NCOA1 (0.37) | GAATSHRALDH1A1HPGDHTR2C | |
| SCHEMBL11629337 | 0.74 | MEN1 (0.56) | POLBGAATSHRALDH1A1HPGD | |
| SCHEMBL11628689 | 0.74 | HTR2C (0.37) | HTR2C | |
| SCHEMBL10328387 | 0.72 | NLRP3 (0.40) | POLBGAATSHRALDH1A1HPGD | |
| SCHEMBL11627756 | 0.70 | POLB (0.30) | POLBGAATSHRALDH1A1HPGD | |
| SCHEMBL11483040 | 0.68 | CYP3A4 (0.39) | POLBGAAKDM4EMAPT | |
| SCHEMBL11623045 | 0.68 | MEN1 (0.37) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL11627586 | 0.68 | ALDH1A1 (0.45) | POLBGAATSHRALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4071562-A | 4,5-Dialkoxy-6 or 7-indanaldehydes | MARION LABORATORIES, INC. (US) | 1978-01-31 | — | — | US | disclosed |
| US-3963723-A | HYPOTENSIVE | MARION LABORATORIES, INC. (US) | 1976-06-15 | — | — | US | disclosed |
| US-3962254-A | HYPOTENSIVE AGENTS | MARION LABORATORIES, INC. (US) | 1976-06-08 | — | — | US | disclosed |