Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 6/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 3/20 | 0.33 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11625348 | 0.93 | MEN1 (0.52) | MEN1KMT2ALMNAPOLBGAA | |
| SCHEMBL11626605 | 0.88 | MEN1 (0.64) | MEN1KMT2ALMNAPOLBGAA | |
| SCHEMBL11626183 | 0.81 | MEN1 (0.50) | MEN1KMT2ALMNAPOLBTSHR | |
| SCHEMBL11625349 | 0.81 | PRMT1 (0.40) | MEN1KMT2ALMNAALDH1A1CYP1A2 | |
| SCHEMBL11866795 | 0.80 | MEN1 (0.49) | MEN1KMT2ALMNAPOLBGAA | |
| SCHEMBL11629474 | 0.75 | LMNA (0.46) | MEN1KMT2ALMNAPOLBTSHR | |
| SCHEMBL11629129 | 0.74 | POLB (0.33) | MEN1KMT2APOLBGAATSHR | |
| SCHEMBL11629132 | 0.73 | HTR2A (0.43) | MEN1KMT2APOLBGAATSHR | |
| SCHEMBL11627431 | 0.73 | ALDH1A1 (0.42) | MEN1KMT2ALMNAPOLBGAA | |
| SCHEMBL10328387 | 0.72 | NLRP3 (0.40) | POLBGAATSHRALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4071562-A | 4,5-Dialkoxy-6 or 7-indanaldehydes | MARION LABORATORIES, INC. (US) | 1978-01-31 | — | — | US | disclosed |
| US-3963723-A | HYPOTENSIVE | MARION LABORATORIES, INC. (US) | 1976-06-15 | — | — | US | disclosed |
| US-3962254-A | HYPOTENSIVE AGENTS | MARION LABORATORIES, INC. (US) | 1976-06-08 | — | — | US | disclosed |