Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 7/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11630194 | 0.83 | ALDH1A1 (0.50) | MAPTALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL6825635 | 0.82 | L3MBTL1 (0.61) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11839824 | 0.82 | KMT2A (0.57) | MAPTALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL11141499 | 0.81 | MAPT (0.51) | MAPTALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL10430183 | 0.81 | GAA (0.62) | MAPTALDH1A1 | |
| SCHEMBL11746097 | 0.80 | MAPT (0.64) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11846059 | 0.80 | MAPT (0.50) | MAPTALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL11631145 | 0.80 | MAPT (0.53) | MAPTALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL9515517 | 0.79 | GAA (0.57) | MAPTALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL11842493 | 0.79 | KMT2A (0.62) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4080461-A | PESTICIDES, FUNGICIDES | SYNTEX (U.S.A.) INC. (US) | 1978-03-21 | — | — | US | disclosed |
| US-4002640-A | ANTIFUNGAL AGENTS | SYNTEX (U.S.A.) INC. (US) | 1977-01-11 | — | — | US | disclosed |