SCHEMBL6825635

SCHEMBL6825635

COc1ccc(NC(=O)C[N+](=O)[O-])cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.61
MEN1 O00255 3/20 0.60
KMT2A Q03164 3/20 0.60
ALDH1A1 P00352 6/20 0.58
HTT P42858 1/20 0.58
SMN1; SMN2 Q16637 4/20 0.56
RAB9A P51151 2/20 0.56
NPC1 O15118 2/20 0.56
MAPT P10636 4/20 0.55
HDAC3 O15379 2/20 0.55
HDAC4 P56524 2/20 0.55
HDAC1 Q13547 2/20 0.55
HDAC7 Q8WUI4 2/20 0.55
HDAC2 Q92769 2/20 0.55
HDAC10 Q969S8 2/20 0.55
HDAC11 Q96DB2 2/20 0.55
HDAC8 Q9BY41 2/20 0.55
HDAC6 Q9UBN7 2/20 0.55
HDAC9 Q9UKV0 2/20 0.55
HDAC5 Q9UQL6 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3170705 0.89 MEN1 (0.50) L3MBTL1MEN1KMT2AALDH1A1HTT
SCHEMBL11630194 0.85 ALDH1A1 (0.50) L3MBTL1MEN1KMT2AALDH1A1HTT
SCHEMBL10655894 0.84 L3MBTL1 (0.67) L3MBTL1MEN1KMT2AALDH1A1HTT
SCHEMBL9515517 0.84 GAA (0.57) L3MBTL1MEN1KMT2AALDH1A1HTT
SCHEMBL8536570 0.82 MEN1 (0.64) L3MBTL1MEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL11629151 0.82 MAPT (0.50) MEN1KMT2AALDH1A1HTTSMN1; SMN2
SCHEMBL1532371 0.81 POLB (0.63) MEN1KMT2AALDH1A1HTTSMN1; SMN2
SCHEMBL11839824 0.81 KMT2A (0.57) MEN1KMT2AALDH1A1HTTSMN1; SMN2
SCHEMBL9313874 0.81 L3MBTL1 (0.76) L3MBTL1MEN1KMT2AALDH1A1HTT
SCHEMBL11141499 0.80 MAPT (0.51) L3MBTL1MEN1KMT2AALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119039170-A Novel continuous production process of 2-amino-4-acetamido anisole and intermediate 徐洪东 2024-11-29 CN claimed
CN-113651713-B Synthesis method of high-purity 2-nitro-4-acetamido anisole 宁夏中盛新科技有限公司 2024-05-14 CN claimed
CN-115583894-B Method and device for continuously producing 2-nitro-4-methoxy acetanilide 浙江迪邦化工有限公司 2024-02-27 CN claimed
CN-116903487-A Method and equipment for continuously preparing 2-nitro-4-acetamido anisole 山东嘉信新材料有限公司 2023-10-20 CN claimed
CN-111704555-B Method for synthesizing 4-methoxy-2-nitroaniline by adopting continuous flow reactor 爱斯特(成都)生物制药股份有限公司 2023-08-01 CN claimed
CN-116143649-A Synthesis method of 2-amino-4-acetamido anisole 宁夏中盛新科技有限公司 2023-05-23 CN claimed
CN-115583894-A Method and device for continuously producing 2-nitro-4-methoxyacetanilide 浙江迪邦化工有限公司 2023-01-10 CN claimed
CN-113770103-B Low-cost washing method of 2-nitro-4-acetamino anisole 宁夏中盛新科技有限公司 2022-08-16 CN claimed
CN-113770103-A Low-cost washing method of 2-nitro-4-acetamino anisole 宁夏中盛新科技有限公司 2021-12-10 CN claimed
CN-113651713-A Synthesis method of high-purity 2-nitro-4-acetamino anisole 宁夏中盛新科技有限公司 2021-11-16 CN claimed
CN-108373424-B Preparation method of 2-amino-4-acetamino anisole 浙江闰土研究院有限公司 2021-03-19 CN claimed
CN-108658051-B Method and device for recovering nitration waste acid and sulfuric acid recovered by method and device 宁夏中盛新科技有限公司 2020-10-30 CN claimed
CN-111704555-A Method for synthesizing 4-methoxy-2-nitroaniline by adopting continuous flow reactor 爱斯特(成都)生物制药股份有限公司 2020-09-25 CN claimed
CN-106242990-B Preparation method of 2-amino-4-acetamino anisole 浙江闰土研究院有限公司 2020-04-28 CN claimed
CN-107746380-B Industrial production method of 2-amino-4-acetamino anisole 宁夏中盛新科技有限公司 2020-04-07 CN claimed
CN-107903182-B Synthesis method of 2-amino-4-acetamino anisole 宁夏中盛新科技有限公司 2020-04-07 CN claimed
CN-1203045-C Method for preparing 4-chlorine-3-nitroanisole YANGZIJIANG PHARMACEUTICAL GRO (CN) 2005-05-25 CN claimed
WO-2004092142-A1 AN IMPROVED PROCESS FOR MANUFACTURE OF SUBSTITUTED BENZIMIDAZOLES IPCA LABORATORIES LIMITED (IN) 2004-10-28 WO claimed
CN-1462737-A Method for preparing 4-chlorine-3-nitroanisole YANGZIJIANG DRUG INDUSTRY CO L (CN) 2003-12-24 CN claimed
CN-120172873-A Continuous industrial production method of 2-nitro-4-acetamido anisole 宁夏中盛新科技有限公司 2025-06-20 CN disclosed
CN-120172873-A Continuous industrial production method of 2-nitro-4-acetamido anisole 宁夏中盛新科技有限公司 2025-06-20 CN disclosed
CN-119039170-A Novel continuous production process of 2-amino-4-acetamido anisole and intermediate 徐洪东 2024-11-29 CN disclosed
CN-113651713-B Synthesis method of high-purity 2-nitro-4-acetamido anisole 宁夏中盛新科技有限公司 2024-05-14 CN disclosed
CN-113651713-B Synthesis method of high-purity 2-nitro-4-acetamido anisole 宁夏中盛新科技有限公司 2024-05-14 CN disclosed
CN-115583894-B Method and device for continuously producing 2-nitro-4-methoxy acetanilide 浙江迪邦化工有限公司 2024-02-27 CN disclosed
CN-115583894-B Method and device for continuously producing 2-nitro-4-methoxy acetanilide 浙江迪邦化工有限公司 2024-02-27 CN disclosed
CN-115583894-B Method and device for continuously producing 2-nitro-4-methoxy acetanilide 浙江迪邦化工有限公司 2024-02-27 CN disclosed
CN-116903487-A Method and equipment for continuously preparing 2-nitro-4-acetamido anisole 山东嘉信新材料有限公司 2023-10-20 CN disclosed
CN-116903487-A Method and equipment for continuously preparing 2-nitro-4-acetamido anisole 山东嘉信新材料有限公司 2023-10-20 CN disclosed
CN-116903487-A Method and equipment for continuously preparing 2-nitro-4-acetamido anisole 山东嘉信新材料有限公司 2023-10-20 CN disclosed
CN-114699939-B Supergravity gas mixing device for gradually cutting bubbles and application thereof 北京化工大学 2023-08-29 CN disclosed
CN-111704555-B Method for synthesizing 4-methoxy-2-nitroaniline by adopting continuous flow reactor 爱斯特(成都)生物制药股份有限公司 2023-08-01 CN disclosed
CN-111704555-B Method for synthesizing 4-methoxy-2-nitroaniline by adopting continuous flow reactor 爱斯特(成都)生物制药股份有限公司 2023-08-01 CN disclosed
CN-116143649-A Synthesis method of 2-amino-4-acetamido anisole 宁夏中盛新科技有限公司 2023-05-23 CN disclosed
CN-116143649-A Synthesis method of 2-amino-4-acetamido anisole 宁夏中盛新科技有限公司 2023-05-23 CN disclosed
CN-115583894-A Method and device for continuously producing 2-nitro-4-methoxyacetanilide 浙江迪邦化工有限公司 2023-01-10 CN disclosed
CN-115583894-A Method and device for continuously producing 2-nitro-4-methoxyacetanilide 浙江迪邦化工有限公司 2023-01-10 CN disclosed
CN-115583894-A Method and device for continuously producing 2-nitro-4-methoxyacetanilide 浙江迪邦化工有限公司 2023-01-10 CN disclosed
CN-113770103-B Low-cost washing method of 2-nitro-4-acetamino anisole 宁夏中盛新科技有限公司 2022-08-16 CN disclosed
CN-113770103-B Low-cost washing method of 2-nitro-4-acetamino anisole 宁夏中盛新科技有限公司 2022-08-16 CN disclosed
CN-113770103-B Low-cost washing method of 2-nitro-4-acetamino anisole 宁夏中盛新科技有限公司 2022-08-16 CN disclosed
CN-114699939-A Hypergravity gas mixing device for cutting bubbles step by step and application thereof 北京化工大学 2022-07-05 CN disclosed
CN-113770103-A Low-cost washing method of 2-nitro-4-acetamino anisole 宁夏中盛新科技有限公司 2021-12-10 CN disclosed
CN-113770103-A Low-cost washing method of 2-nitro-4-acetamino anisole 宁夏中盛新科技有限公司 2021-12-10 CN disclosed
CN-113770103-A Low-cost washing method of 2-nitro-4-acetamino anisole 宁夏中盛新科技有限公司 2021-12-10 CN disclosed
CN-113651713-A Synthesis method of high-purity 2-nitro-4-acetamino anisole 宁夏中盛新科技有限公司 2021-11-16 CN disclosed
CN-113651713-A Synthesis method of high-purity 2-nitro-4-acetamino anisole 宁夏中盛新科技有限公司 2021-11-16 CN disclosed
CN-113651713-A Synthesis method of high-purity 2-nitro-4-acetamino anisole 宁夏中盛新科技有限公司 2021-11-16 CN disclosed
CN-108373424-B Preparation method of 2-amino-4-acetamino anisole 浙江闰土研究院有限公司 2021-03-19 CN disclosed
CN-108373424-B Preparation method of 2-amino-4-acetamino anisole 浙江闰土研究院有限公司 2021-03-19 CN disclosed
CN-108658051-B Method and device for recovering nitration waste acid and sulfuric acid recovered by method and device 宁夏中盛新科技有限公司 2020-10-30 CN disclosed
CN-111704555-A Method for synthesizing 4-methoxy-2-nitroaniline by adopting continuous flow reactor 爱斯特(成都)生物制药股份有限公司 2020-09-25 CN disclosed
CN-111704555-A Method for synthesizing 4-methoxy-2-nitroaniline by adopting continuous flow reactor 爱斯特(成都)生物制药股份有限公司 2020-09-25 CN disclosed
CN-111269135-A Production process of 2-amino-4-acetamidophenyl ether 中卫市鑫三元化工有限公司 2020-06-12 CN disclosed
CN-106242990-B Preparation method of 2-amino-4-acetamino anisole 浙江闰土研究院有限公司 2020-04-28 CN disclosed
CN-106242990-B Preparation method of 2-amino-4-acetamino anisole 浙江闰土研究院有限公司 2020-04-28 CN disclosed
CN-107903182-B Synthesis method of 2-amino-4-acetamino anisole 宁夏中盛新科技有限公司 2020-04-07 CN disclosed
CN-107903182-B Synthesis method of 2-amino-4-acetamino anisole 宁夏中盛新科技有限公司 2020-04-07 CN disclosed
CN-107746380-B Industrial production method of 2-amino-4-acetamino anisole 宁夏中盛新科技有限公司 2020-04-07 CN disclosed
CN-107746380-B Industrial production method of 2-amino-4-acetamino anisole 宁夏中盛新科技有限公司 2020-04-07 CN disclosed
US-9463450-B1 Polymeric acid catalysis COMPACT MEMBRANE SYSTEMS, INC. (US) 2016-10-11 US disclosed
US-20160279623-A1 POLYMERIC ACID CATALYSIS COMPACT MEMBRANE SYSTEMS, INC. (US) 2016-09-29 US disclosed
CN-103641734-B A kind of method of selectivity synthesis aromatic hydrocarbons nitro-compound SHAANXI NORMAL UNIVERSITY (CN) 2015-10-28 CN disclosed
CN-103641734-A Method for selectively synthesizing aromatic nitro compound UNIV SHAANXI NORMAL 2014-03-19 CN disclosed
CN-101309917-B Stomach H with enhanced therapeutic properties+,K+-deuteration inhibitors of ATPase AUSPEX PHARMACEUTICALS INC 2013-09-11 CN disclosed
CN-101309917-A Stomach H with enhanced therapeutic properties+,K+-deuteration inhibitors of ATPase AUSPEX PHARMACEUTICALS INC (US) 2008-11-19 CN disclosed
CN-1203045-C Method for preparing 4-chlorine-3-nitroanisole YANGZIJIANG PHARMACEUTICAL GRO (CN) 2005-05-25 CN disclosed
WO-2004092142-A1 AN IMPROVED PROCESS FOR MANUFACTURE OF SUBSTITUTED BENZIMIDAZOLES IPCA LABORATORIES LIMITED (IN) 2004-10-28 WO disclosed
EP-0009794-A1 Process for the preparation of nitro acetanilides BASF Aktiengesellschaft (DE) 1980-04-16 EP disclosed
EP-0009794-A1 Process for the preparation of nitro acetanilides BASF Aktiengesellschaft (DE) 1980-04-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160279623-A1 POLYMERIC ACID CATALYSIS HNRNPF, PFAS, PFKFB3 L3MBTL1 4796/4885MEN1 3258/4885KMT2A 2544/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.