Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 5/20 | 0.37 |
| ▸ | CES1 | P23141 | 5/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11628326 | 0.82 | MAPK1 (0.43) | LMNACES2CES1TSHRALDH1A1 | |
| SCHEMBL9718661 | 0.79 | LMNA (0.40) | LMNACES2CES1TSHRDAO | |
| SCHEMBL8151048 | 0.78 | LMNA (0.48) | LMNACES2CES1TSHRDAO | |
| SCHEMBL28760495 | 0.76 | AKR1C1 (0.43) | LMNATSHRALDH1A1MAPTCYP2C19 | |
| SCHEMBL9718676 | 0.75 | LMNA (0.46) | LMNACES2CES1TSHRDAO | |
| SCHEMBL14421361 | 0.75 | LMNA (0.46) | LMNACES2CES1TSHRDAO | |
| SCHEMBL9052323 | 0.73 | LMNA (0.44) | LMNACES2CES1TSHRDAO | |
| SCHEMBL402908 | 0.73 | CETP (0.46) | LMNACES2CES1TSHRDAO | |
| Hydrochloric Acid SCHEMBL9053050 | 0.72 | LMNA (0.43) | LMNACES2CES1TSHRDAO | |
| SCHEMBL20228048 | 0.70 | SIGMAR1 (0.44) | LMNATSHRALDH1A1GAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4116665-A | Method of regulating the growth of aquatic weeds with pyridine derivatives | ELI LILLY AND COMPANY (US) | 1978-09-26 | — | — | US | disclosed |
| US-3962269-A | ANALGESICS | ELI LILLY AND COMPANY (US) | 1976-06-08 | — | — | US | disclosed |