Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.55 |
| ▸ | NAMPT | P43490 | 1/20 | 0.54 |
| ▸ | NT5E | P21589 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | ABL1 | P00519 | 2/20 | 0.53 |
| ▸ | JAK2 | O60674 | 1/20 | 0.53 |
| ▸ | TYK2 | P29597 | 1/20 | 0.53 |
| ▸ | STAT3 | P40763 | 2/20 | 0.51 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6657635 | 0.85 | TRPV1 (0.76) | GAALMNAMAPK1ALDH1A1TP53 | |
| SCHEMBL19242053 | 0.82 | GAA (1.00) | GAALMNAMAPK1ALDH1A1TP53 | |
| SCHEMBL3271513 | 0.80 | RAB9A (0.77) | GAALMNAMAPK1ALDH1A1TP53 | |
| SCHEMBL1898755 | 0.78 | GAA (0.91) | GAALMNAMAPK1ALDH1A1TP53 | |
| SCHEMBL30828555 | 0.78 | GAA (0.70) | GAALMNAMAPK1ALDH1A1TP53 | |
| SCHEMBL11617697 | 0.77 | MAPK1 (1.00) | GAALMNAMAPK1ALDH1A1TP53 | |
| SCHEMBL19241697 | 0.77 | GAA (0.88) | GAALMNAMAPK1ALDH1A1TP53 | |
| SCHEMBL8298025 | 0.76 | GAA (0.79) | GAAMAPK1KDM4EL3MBTL1HTT | |
| SCHEMBL7461375 | 0.76 | GAA (0.79) | GAALMNAMAPK1ALDH1A1TP53 | |
| SCHEMBL23734986 | 0.75 | GAA (0.85) | GAALMNAMAPK1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4069224-A | N-(PYRIDYLALKYL)BENZAMIDES, IMPROVE PRODUCTION OF PROSTAGLANDINS IN MAMMALS | THE UPJOHN COMPANY (US) | 1978-01-17 | — | — | US | disclosed |