Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.53 |
| ▸ | NISCH | Q9Y2I1 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.48 |
| ▸ | HTR1B | P28222 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTR1D | P28221 | 3/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11627477 | 0.81 | ADRA1A (0.63) | TAAR1ADRA1ANISCHMAPK1LMNA | |
| Maleic Acid SCHEMBL11630324 | 0.74 | ADRA1A (0.52) | TAAR1ADRA1ANISCHMAPK1LMNA | |
| SCHEMBL11632111 | 0.73 | ADRA1A (0.53) | TAAR1ADRA1ANISCHMAPK1LMNA | |
| SCHEMBL26078336 | 0.72 | ADRA1A (0.52) | TAAR1ADRA1ANISCHMAPK1LMNA | |
| SCHEMBL25267273 | 0.71 | KDM4E (0.59) | ADRA1AMAPK1LMNAMAPTCYP1A2 | |
| SCHEMBL17887761 | 0.71 | TAAR1 (0.64) | TAAR1ADRA1ANISCHMAPK1LMNA | |
| SCHEMBL27738503 | 0.70 | TAAR1 (0.56) | TAAR1ADRA1ANISCHMAPK1LMNA | |
| Naphazoline SCHEMBL34532 | 0.70 | TAAR1 (1.00) | TAAR1ADRA1ANISCHMAPK1LMNA | |
| Naphazoline SCHEMBL29369882 | 0.70 | TAAR1 (1.00) | TAAR1ADRA1ANISCHMAPK1LMNA | |
| SCHEMBL954827 | 0.69 | TAAR1 (0.68) | TAAR1ADRA1ANISCHMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4081544-A | ANTIDEPRESSANTS | SCHERING CORPORATION (US) | 1978-03-28 | — | — | US | claimed |
| US-4081544-A | ANTIDEPRESSANTS | SCHERING CORPORATION (US) | 1978-03-28 | — | — | US | disclosed |
| US-3932431-A | ANTIDEPRESSANT, ANTIINFLAMMATORY | SCHERING CORPORATION (US) | 1976-01-13 | — | — | US | disclosed |