Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 8/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11627477 | 0.92 | ADRA1A (0.63) | ADRA1AADRA1BADRA1DTAAR1ADRA2A | |
| Maleic Acid SCHEMBL11630324 | 0.81 | ADRA1A (0.52) | ADRA1AADRA1BADRA1DTAAR1ADRA2A | |
| SCHEMBL21666537 | 0.77 | KDM4E (0.54) | ADRA1AADRA1BADRA1DMAPK1LMNA | |
| SCHEMBL26078336 | 0.76 | ADRA1A (0.52) | ADRA1AADRA1BADRA1DTAAR1ADRA2A | |
| SCHEMBL7012713 | 0.76 | TAAR1 (0.49) | ADRA1AADRA1BADRA1DTAAR1ADRA2A | |
| SCHEMBL7013543 | 0.75 | TAAR1 (0.46) | ADRA1AADRA1BADRA1DTAAR1ADRA2A | |
| SCHEMBL11630134 | 0.73 | TAAR1 (0.53) | ADRA1AADRA1BADRA1DTAAR1ADRA2A | |
| SCHEMBL954650 | 0.72 | TAAR1 (0.60) | ADRA1AADRA1BADRA1DTAAR1ADRA2A | |
| SCHEMBL11630545 | 0.71 | HTR7 (0.39) | ADRA1AADRA1BADRA1DADRA2AADRA2B | |
| SCHEMBL11597510 | 0.71 | TAAR1 (0.79) | ADRA1AADRA1BADRA1DTAAR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4081544-A | ANTIDEPRESSANTS | SCHERING CORPORATION (US) | 1978-03-28 | — | — | US | disclosed |
| US-3932431-A | ANTIDEPRESSANT, ANTIINFLAMMATORY | SCHERING CORPORATION (US) | 1976-01-13 | — | — | US | disclosed |