Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28924092 | 1.00 | ALDH1A1 (0.53) | ALDH1A1LMNAKMT2ATDP1MAPT | |
| SCHEMBL9478771 | 0.84 | ESR1 (0.57) | ALDH1A1LMNAKMT2ATDP1MAPT | |
| SCHEMBL8462360 | 0.84 | TSHR (0.62) | ALDH1A1LMNAKMT2ATDP1MAPT | |
| SCHEMBL21473833 | 0.84 | TSHR (0.62) | ALDH1A1LMNAKMT2ATDP1MAPT | |
| SCHEMBL11632540 | 0.83 | MEN1 (0.49) | ALDH1A1KMT2AMAPTTP53TSHR | |
| SCHEMBL11631541 | 0.81 | ALDH1A1 (0.49) | ALDH1A1LMNAKMT2ATDP1MAPT | |
| SCHEMBL9502663 | 0.81 | CYP2D6 (0.55) | ALDH1A1LMNAKMT2ATDP1GAA | |
| SCHEMBL11777806 | 0.80 | MEN1 (0.59) | ALDH1A1LMNAKMT2AMAPTGAA | |
| SCHEMBL11164729 | 0.79 | ALDH1A1 (0.50) | ALDH1A1LMNAKMT2ATDP1MAPT | |
| SCHEMBL5363086 | 0.78 | ALDH1A1 (0.63) | ALDH1A1LMNAKMT2ATDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4085277-A | BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1978-04-18 | — | — | US | disclosed |
| US-4001225-A | Pyridyl substituted 7-αesters of 3 heterothio 7-acetamido cephalosporanic acids | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1977-01-04 | — | — | US | disclosed |
| US-4000133-A | BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-12-28 | — | — | US | disclosed |