Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | KLK7 | P49862 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9503442 | 0.87 | CYP2D6 (0.66) | CYP2D6KMT2ALMNAKLK7ALDH1A1 | |
| SCHEMBL28924092 | 0.81 | ALDH1A1 (0.53) | KMT2ALMNATDP1HTTGAA | |
| SCHEMBL11630201 | 0.81 | ALDH1A1 (0.53) | KMT2ALMNATDP1HTTGAA | |
| Niacin SCHEMBL9502658 | 0.78 | SMN1; SMN2 (0.53) | KMT2ALMNAHTTSMN1; SMN2HPGD | |
| SCHEMBL4158522 | 0.75 | PKM (0.62) | KMT2ALMNAHTTKLK7ALDH1A1 | |
| SCHEMBL4162007 | 0.75 | PKM (0.62) | KMT2ALMNAHTTKLK7ALDH1A1 | |
| SCHEMBL4158526 | 0.75 | PKM (0.62) | KMT2ALMNAHTTKLK7ALDH1A1 | |
| SCHEMBL354041 | 0.75 | TSHR (0.76) | KMT2ASMN1; SMN2GAAL3MBTL1CYP2C9 | |
| SCHEMBL9478771 | 0.75 | ESR1 (0.57) | KMT2ALMNATDP1HTTGAA | |
| Iodide SCHEMBL15903217 | 0.74 | TSHR (0.74) | KMT2ASMN1; SMN2GAACYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376852-B1 | MICROGRANULES ESSENTIALLY CONSISTING OF TRIGLYCERIDES OF SATURATED FATTY ACIDS LOADED WITH AN ACTIVE SUBSTANCE, AND THEIR TOPICAL THERAPEUTICAL USE | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA (FR) | 1993-06-23 | — | — | EP | claimed |