Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21666537 | 0.75 | KDM4E (0.54) | HTR7ADRA1DADRA1AADRA1B | |
| SCHEMBL11627477 | 0.73 | ADRA1A (0.63) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL12079396 | 0.71 | KDM4E (0.45) | BRD4 | |
| SCHEMBL11632111 | 0.71 | ADRA1A (0.53) | HTR7ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL2514598 | 0.70 | CYP1A2 (0.63) | ADRA2AADRA2BADRA2CHTR1DADRA1D | |
| SCHEMBL4777973 | 0.69 | KDM4E (0.50) | BRD4 | |
| SCHEMBL24888335 | 0.69 | KDM4E (0.54) | HTR7ADRA1DADRA1AADRA1B | |
| SCHEMBL22910530 | 0.68 | LTA4H (0.47) | HTR7ADRA1DADRA1AADRA1BBRD4 | |
| SCHEMBL14678660 | 0.66 | KDM4E (0.46) | ADRA2AADRA2BADRA2CBRD4 | |
| SCHEMBL27834816 | 0.66 | KDM4E (0.46) | HTR7ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4081544-A | ANTIDEPRESSANTS | SCHERING CORPORATION (US) | 1978-03-28 | — | — | US | disclosed |
| US-3932431-A | ANTIDEPRESSANT, ANTIINFLAMMATORY | SCHERING CORPORATION (US) | 1976-01-13 | — | — | US | disclosed |