Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.39 |
| ▸ | HTR2A | P28223 | 4/20 | 0.39 |
| ▸ | HTR2C | P28335 | 4/20 | 0.39 |
| ▸ | HTR2B | P41595 | 4/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11631967 | 0.94 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1MAPTGAAKDM4E | |
| SCHEMBL11634610 | 0.92 | L3MBTL1 (0.45) | L3MBTL1ALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL11744846 | 0.91 | L3MBTL1 (0.51) | L3MBTL1ALDH1A1MAPTGAAKDM4E | |
| SCHEMBL11629077 | 0.88 | L3MBTL1 (0.56) | L3MBTL1ALDH1A1MAPTGAAKDM4E | |
| SCHEMBL11630520 | 0.86 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1MAPTKDM4EOPRM1 | |
| SCHEMBL11633867 | 0.86 | L3MBTL1 (0.54) | L3MBTL1ALDH1A1MAPTGAAKDM4E | |
| SCHEMBL11744576 | 0.85 | L3MBTL1 (0.53) | L3MBTL1ALDH1A1MAPTGAAKDM4E | |
| SCHEMBL11634992 | 0.85 | L3MBTL1 (0.53) | L3MBTL1ALDH1A1MAPTGAAKDM4E | |
| SCHEMBL11635081 | 0.83 | L3MBTL1 (0.56) | L3MBTL1ALDH1A1MAPTGAALMNA | |
| SCHEMBL11628957 | 0.83 | L3MBTL1 (0.51) | L3MBTL1ALDH1A1MAPTGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4077958-A | ANTIDEPRESSANTS | E. R. SQUIBB & SONS, INC. (US) | 1978-03-07 | — | — | US | disclosed |
| US-4007191-A | ANTIDEPRESSANT | E. R. SQUIBB & SONS, INC. (US) | 1977-02-08 | — | — | US | disclosed |