Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11629536 | 0.94 | SIGMAR1 (0.46) | L3MBTL1OPRL1SIGMAR1DRD2ALDH1A1 | |
| SCHEMBL11629977 | 0.93 | SIGMAR1 (0.46) | L3MBTL1OPRL1SIGMAR1DRD2ALDH1A1 | |
| SCHEMBL11630996 | 0.93 | SIGMAR1 (0.46) | L3MBTL1OPRL1SIGMAR1DRD2ALDH1A1 | |
| SCHEMBL11634977 | 0.91 | L3MBTL1 (0.47) | L3MBTL1OPRL1DRD2ALDH1A1MAPT | |
| SCHEMBL11633969 | 0.88 | L3MBTL1 (0.47) | L3MBTL1DRD2ALDH1A1MAPTPOLB | |
| SCHEMBL11629858 | 0.88 | L3MBTL1 (0.44) | L3MBTL1OPRL1SIGMAR1POLBMEN1 | |
| SCHEMBL11629569 | 0.88 | L3MBTL1 (0.44) | L3MBTL1DRD2ALDH1A1MAPTPOLB | |
| SCHEMBL11630316 | 0.87 | OPRM1 (0.52) | L3MBTL1OPRL1SIGMAR1DRD2LMNA | |
| SCHEMBL11633475 | 0.86 | L3MBTL1 (0.45) | L3MBTL1OPRL1DRD2ALDH1A1MAPT | |
| SCHEMBL11744846 | 0.86 | L3MBTL1 (0.51) | L3MBTL1OPRL1SIGMAR1DRD2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4077958-A | ANTIDEPRESSANTS | E. R. SQUIBB & SONS, INC. (US) | 1978-03-07 | — | — | US | disclosed |
| US-4007191-A | ANTIDEPRESSANT | E. R. SQUIBB & SONS, INC. (US) | 1977-02-08 | — | — | US | disclosed |