Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11633867 | 0.97 | L3MBTL1 (0.54) | L3MBTL1SIGMAR1GRIN1GRIN2BDRD4 | |
| SCHEMBL11629077 | 0.93 | L3MBTL1 (0.56) | L3MBTL1DRD4ALDH1A1MAPTKDM4E | |
| SCHEMBL11629421 | 0.89 | L3MBTL1 (0.48) | L3MBTL1SIGMAR1DRD4ALDH1A1MAPT | |
| SCHEMBL11635081 | 0.88 | L3MBTL1 (0.56) | L3MBTL1ALDH1A1MAPTGAA | |
| SCHEMBL11632598 | 0.88 | L3MBTL1 (0.49) | L3MBTL1SIGMAR1DRD4ALDH1A1MAPT | |
| SCHEMBL11631967 | 0.87 | L3MBTL1 (0.48) | L3MBTL1SIGMAR1ALDH1A1MAPTKDM4E | |
| SCHEMBL11628957 | 0.86 | L3MBTL1 (0.51) | L3MBTL1DRD4ALDH1A1MAPTKDM4E | |
| SCHEMBL11633446 | 0.86 | L3MBTL1 (0.44) | L3MBTL1SIGMAR1GRIN1GRIN2BALDH1A1 | |
| SCHEMBL11630749 | 0.85 | L3MBTL1 (0.50) | L3MBTL1SIGMAR1ALDH1A1MAPTKDM4E | |
| SCHEMBL11630627 | 0.84 | HTR7 (0.61) | L3MBTL1DRD4ALDH1A1MAPTHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4007191-A | ANTIDEPRESSANT | E. R. SQUIBB & SONS, INC. (US) | 1977-02-08 | — | — | US | disclosed |