SCHEMBL3994643

SCHEMBL3994643

Fc1cc(CI)ccn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7413054 0.82
SCHEMBL12553823 0.77
SCHEMBL1348600 0.77
SCHEMBL2642495 0.77
SCHEMBL29893902 0.77
SCHEMBL501592 0.77
SCHEMBL116309 0.77
SCHEMBL6468413 0.77
SCHEMBL2642497 0.77
Hydrochloric Acid SCHEMBL1413435 0.76 LOXL2 (0.96)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015175855-A1 CHEMOKINE CXCR4 AND CCR5 RECEPTOR MODULATORS AND USED RELATED THERETO EMORY UNIVERSITY (US) 2015-11-19 WO disclosed
US-7553969-B1 Substituted phenethylamine derivatives CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2009-06-30 US disclosed
CN-1343219-A Substituted phenethylamine derivatives CHUGAI PHARMACEUTICAL CO LTD (JP) 2002-04-03 CN disclosed
EP-1149843-A1 SUBSTITUTED PHENETHYLAMINE DERIVATIVES CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2001-10-31 EP disclosed
US-6214847-B1 TREATMENT OF COGNITIVE OR NEUROLOGICAL DYSFUNCTION DUPONT PHARMACEUTICALS COMPANY 2001-04-10 US disclosed
EP-1003722-A1 CRYSTALLINE 10,10-BIS((2-FLUORO-4-PYRIDINYL)METHYL)-9(10H)-ANTHRACENONE AND AN IMPROVED PROCESS FOR PREPARING THE SAME Du Pont Pharmaceuticals Company (US) 2000-05-31 EP disclosed
WO-1999009010-A1 CRYSTALLINE 10,10-BIS((2-FLUORO-4-PYRIDINYL)METHYL)-9(10H)-ANTHRACENONE AND AN IMPROVED PROCESS FOR PREPARING THE SAME DU PONT PHARMACEUTICALS COMPANY (US) 1999-02-25 WO disclosed