Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10370952 | 0.83 | ALDH1A1 (0.49) | L3MBTL1ALDH1A1HTTNPSR1POLB | |
| SCHEMBL637183 | 0.82 | SLC6A2 (0.57) | L3MBTL1ALDH1A1HTTNPSR1CYP1A2 | |
| SCHEMBL11631375 | 0.80 | L3MBTL1 (0.62) | L3MBTL1ALDH1A1HTTNPSR1CYP1A2 | |
| SCHEMBL11729549 | 0.80 | ALDH1A1 (0.53) | L3MBTL1ALDH1A1HTTPOLBATM | |
| SCHEMBL11388119 | 0.79 | ALDH1A1 (0.50) | L3MBTL1ALDH1A1PKMHTTNPSR1 | |
| Hydrochloric Acid SCHEMBL28544066 | 0.78 | L3MBTL1 (0.60) | L3MBTL1ALDH1A1HTTNPSR1CYP1A2 | |
| SCHEMBL5429300 | 0.78 | SLC6A2 (0.48) | ALDH1A1HTTNPSR1CYP1A2POLB | |
| SCHEMBL24110401 | 0.78 | ALDH1A1 (0.47) | L3MBTL1ALDH1A1PKMHTTNPSR1 | |
| SCHEMBL14405606 | 0.76 | MAPT (0.42) | L3MBTL1ALDH1A1HTTMAPTSMN1; SMN2 | |
| SCHEMBL17842026 | 0.76 | MAPT (0.42) | L3MBTL1ALDH1A1HTTMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4081544-A | ANTIDEPRESSANTS | SCHERING CORPORATION (US) | 1978-03-28 | — | — | US | disclosed |
| US-3932431-A | ANTIDEPRESSANT, ANTIINFLAMMATORY | SCHERING CORPORATION (US) | 1976-01-13 | — | — | US | disclosed |