Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | SCN1A | P35498 | 1/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.44 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5429300 | 0.88 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3ALDH1A1HTT | |
| SCHEMBL11729549 | 0.86 | ALDH1A1 (0.53) | SLC6A2SLC6A4SLC6A3ALDH1A1HTT | |
| SCHEMBL10370952 | 0.86 | ALDH1A1 (0.49) | SLC6A2SLC6A4SLC6A3ALDH1A1HTT | |
| SCHEMBL11631375 | 0.86 | L3MBTL1 (0.62) | SLC6A2SLC6A4SLC6A3ALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL28544066 | 0.84 | L3MBTL1 (0.60) | SLC6A2SLC6A4SLC6A3ALDH1A1HTT | |
| SCHEMBL2132845 | 0.82 | GAA (0.49) | SLC6A2SLC6A4SLC6A3ALDH1A1HTT | |
| SCHEMBL11632012 | 0.82 | L3MBTL1 (0.43) | SLC6A2SLC6A4SLC6A3ALDH1A1HTT | |
| SCHEMBL11632105 | 0.82 | ALDH1A1 (0.56) | SLC6A3ALDH1A1HTTL3MBTL1GAA | |
| SCHEMBL11625524 | 0.82 | GAA (0.48) | SLC6A2SLC6A4SLC6A3ALDH1A1L3MBTL1 | |
| SCHEMBL25998638 | 0.82 | L3MBTL1 (0.40) | SLC6A2SLC6A4SLC6A3ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101786982-A | Method for synthetizing 2-pyridyl benzyl cyanide | UNIV EAST CHINA NORMAL | 2010-07-28 | — | — | CN | claimed |
| US-20030049807-A1 | Micro-organism possessing enantioselective and regioselective nitrile hydratase/amidase activities | INSTITUTO BIOCHIMICO ITALIANO GIOVANNI LOREZINI S.P.A. (IT) | 2003-03-13 | — | — | US | claimed |
| EP-1291435-A2 | A micro-organism possessing enantioselective and regioselective nitrile hydratase/amidase activities | ISTITUTO BIOCHIMICO ITALIANO GIOVANNI LORENZINI S.p.A. (IT) | 2003-03-12 | — | — | EP | claimed |
| US-4072808-A | Process for preparing elastomers for pressure-sensitive adhesive application | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1978-02-07 | — | — | US | claimed |
| US-20210380548-A1 | Fused [1,2,4]Thiadiazine Derivatives Which Act as KAT Inhibitors of the MYST Family | CTXT PTY LIMITED (AU) | 2021-12-09 | — | — | US | disclosed |
| US-20210380548-A1 | Fused [1,2,4]Thiadiazine Derivatives Which Act as KAT Inhibitors of the MYST Family | CTXT PTY LIMITED (AU) | 2021-12-09 | — | — | US | disclosed |
| EP-3676266-A1 | FUSED [1,2,4]THIADIAZINE DERIVATIVES WHICH ACT AS KAT INHIBITORS OF THE MYST FAMILY | Ctxt Pty Ltd (AU) | 2020-07-08 | — | — | EP | disclosed |
| WO-2019043139-A1 | FUSED [1,2,4]THIADIAZINE DERIVATIVES WHICH ACT AS KAT INHIBITORS OF THE MYST FAMILY | CTXT PTY LIMITED (AU) | 2019-03-07 | — | — | WO | disclosed |
| WO-2019043139-A1 | FUSED [1,2,4]THIADIAZINE DERIVATIVES WHICH ACT AS KAT INHIBITORS OF THE MYST FAMILY | CTXT PTY LIMITED (AU) | 2019-03-07 | — | — | WO | disclosed |
| US-8552030-B2 | Process for the preparation of d-threo-ritalinic acid hydrochloride by resolution of dl-threo-ritalinic acid using chiral carboxylic acid | MALLADI DRUGS & PHARMACEUTICALS LTD. (IN) | 2013-10-08 | — | — | US | disclosed |
| EP-1506961-B1 | Processes for resolving piperidyl acetamide stereoisomers | CELGENE CORP (US) | 2012-02-22 | — | — | EP | disclosed |
| US-8008278-B2 | Diarylmethyl and related compounds | THERAVANCE, INC. (US) | 2011-08-30 | — | — | US | disclosed |
| US-4081544-A | ANTIDEPRESSANTS | SCHERING CORPORATION (US) | 1978-03-28 | — | — | US | disclosed |
| US-4073921-A | FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1978-02-14 | — | — | US | disclosed |
| US-4072808-A | Process for preparing elastomers for pressure-sensitive adhesive application | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1978-02-07 | — | — | US | disclosed |
| US-4025524-A | ANTISPASMODIC, ANTIARRHYTHMIC, VIRICIDES | G. D. SEARLE & CO. (US) | 1977-05-24 | — | — | US | disclosed |
| US-3984557-A | 1-R-3-PYRROLIDINYL-A-PHENYL-A-(2-PYRIDYL) ACETAMIDES, -ACETONITRILES, AND -METHANES | A. H. ROBINS COMPANY, INCORPORATED (US) | 1976-10-05 | — | — | US | disclosed |
| US-3956344-A | Process for the production of substituted 2-benzoylpyridines | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1976-05-11 | — | — | US | disclosed |
| US-3932431-A | ANTIDEPRESSANT, ANTIINFLAMMATORY | SCHERING CORPORATION (US) | 1976-01-13 | — | — | US | disclosed |
| US-3932431-A | ANTIDEPRESSANT, ANTIINFLAMMATORY | SCHERING CORPORATION (US) | 1976-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210380548-A1 | Fused [1,2,4]Thiadiazine Derivatives Which Act as KAT Inhibitors of the MYST Family | KAT5, KAT6A, KAT2A | SLC6A2 3963/4885SLC6A4 4183/4885SLC6A3 4075/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.