Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | HPGD | P15428 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | INSR | P06213 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10452715 | 0.85 | ALDH1A1 (0.42) | KMT2AHPGDMEN1ALDH1A1MAPT | |
| SCHEMBL11630830 | 0.83 | MAPT (0.46) | KMT2AHPGDMEN1ALDH1A1MAPT | |
| SCHEMBL11633671 | 0.79 | ALDH1A1 (0.41) | KMT2AHPGDMEN1ALDH1A1MAPT | |
| SCHEMBL11631598 | 0.79 | NPC1 (0.41) | KMT2AHPGDMEN1ALDH1A1MAPT | |
| SCHEMBL11634647 | 0.77 | ALDH1A1 (0.44) | KMT2AMEN1ALDH1A1MAPTRAB9A | |
| SCHEMBL9099294 | 0.73 | SLC6A2 (0.41) | SMN1; SMN2NPSR1CYP3A4 | |
| SCHEMBL6616381 | 0.64 | AHR (0.34) | AHR | |
| SCHEMBL2709215 | 0.62 | AHR (0.50) | KMT2AHPGDMEN1ALDH1A1MAPT | |
| SCHEMBL6414970 | 0.62 | LDHA (0.43) | ALDH1A1GAARECQLKDM4ESMN1; SMN2 | |
| SCHEMBL1806482 | 0.62 | ALDH1A1 (0.57) | KMT2AHPGDMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4085118-A | 5-(5-Halogenatedphenyl-2-furanyl)dihydro-2(3H)-furanones | MORTON-NORWICH PRODUCTS, INC. (US) | 1978-04-18 | — | — | US | claimed |
| US-4085118-A | 5-(5-Halogenatedphenyl-2-furanyl)dihydro-2(3H)-furanones | MORTON-NORWICH PRODUCTS, INC. (US) | 1978-04-18 | — | — | US | disclosed |