Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11631598 | 0.85 | NPC1 (0.41) | ALDH1A1KDM4EMAPTGAAHPGD | |
| SCHEMBL10452715 | 0.85 | ALDH1A1 (0.42) | ALDH1A1KDM4EMAPTSMN1; SMN2GAA | |
| SCHEMBL11633129 | 0.79 | KMT2A (0.41) | ALDH1A1TSHRKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL11630830 | 0.75 | MAPT (0.46) | ALDH1A1KDM4EMAPTSMN1; SMN2GAA | |
| SCHEMBL11634647 | 0.71 | ALDH1A1 (0.44) | ALDH1A1TSHRMAPTSMN1; SMN2GAA | |
| SCHEMBL5963207 | 0.67 | ALDH1A1 (0.58) | ALDH1A1TSHRKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL16765776 | 0.65 | MAPT (0.39) | ALDH1A1TSHRKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL9712225 | 0.63 | POLB (0.44) | ALDH1A1KDM4EMAPTGAAHPGD | |
| SCHEMBL7259690 | 0.62 | MEN1 (0.44) | ALDH1A1KDM4EHPGDHSD17B10NPC1 | |
| SCHEMBL6615671 | 0.61 | ACHE (0.53) | ALDH1A1KDM4ESMN1; SMN2HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4085118-A | 5-(5-Halogenatedphenyl-2-furanyl)dihydro-2(3H)-furanones | MORTON-NORWICH PRODUCTS, INC. (US) | 1978-04-18 | — | — | US | claimed |
| US-4085118-A | 5-(5-Halogenatedphenyl-2-furanyl)dihydro-2(3H)-furanones | MORTON-NORWICH PRODUCTS, INC. (US) | 1978-04-18 | — | — | US | disclosed |