Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | DRD3 | P35462 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | DRD4 | P21917 | 2/20 | 0.54 |
| ▸ | HRH2 | P25021 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HRH1 | P35367 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11633250 | 0.93 | HTR7 (0.55) | HTR7KDM4EMAPK1LMNAHTT | |
| SCHEMBL11631127 | 0.89 | HTR7 (0.58) | HTR7KDM4EMAPK1LMNAHTT | |
| SCHEMBL11630693 | 0.80 | KDM4E (0.60) | HTR7KDM4EMAPK1LMNAHTT | |
| SCHEMBL11633665 | 0.78 | DRD4 (0.53) | HTR7KDM4ELMNAHTTDRD2 | |
| SCHEMBL14454750 | 0.75 | HTR2C (0.54) | HTR7DRD2DRD3HRH1 | |
| SCHEMBL9225440 | 0.74 | MAPK1 (0.81) | HTR7KDM4EMAPK1LMNAHTT | |
| SCHEMBL5307095 | 0.74 | DRD2 (0.69) | HTR7KDM4EMAPK1LMNAHTT | |
| SCHEMBL11524917 | 0.74 | HTR2C (0.52) | HTR7DRD2DRD3ALDH1A1HRH1 | |
| SCHEMBL6031726 | 0.74 | MAPK1 (0.80) | HTR7KDM4EMAPK1LMNAHTT | |
| Bromide SCHEMBL6575673 | 0.73 | MAPK1 (0.78) | HTR7KDM4EMAPK1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4130646-A | SEDATIVE, MUSCLE RELAXANT, TRANQUILIZER | E. R. SQUIBB & SONS, INC. (US) | 1978-12-19 | — | — | US | disclosed |