Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11633392 | 1.00 | CYP11B1 (0.43) | CYP11B1CYP11B2POLBCTDSP1TDP1 | |
| SCHEMBL11633402 | 1.00 | CYP11B1 (0.43) | CYP11B1CYP11B2POLBCTDSP1TDP1 | |
| SCHEMBL11635085 | 0.82 | ALDH1A1 (0.52) | CYP11B1CYP11B2CYP19A1KMT2A | |
| SCHEMBL11635397 | 0.78 | ADRA2C (0.60) | TDP1CYP19A1TSHRKMT2AADRA2C | |
| SCHEMBL11635395 | 0.78 | ADRA2C (0.60) | TDP1CYP19A1TSHRKMT2AADRA2C | |
| SCHEMBL11635400 | 0.78 | ADRA2C (0.60) | TDP1CYP19A1TSHRKMT2AADRA2C | |
| SCHEMBL11635026 | 0.73 | AGER (0.48) | CYP11B1CYP11B2POLBCYP19A1KMT2A | |
| SCHEMBL11631263 | 0.73 | AGER (0.48) | CYP11B1CYP11B2POLBCYP19A1KMT2A | |
| SCHEMBL28739424 | 0.72 | ADRA2C (0.56) | CYP11B1CYP11B2POLBCTDSP1TDP1 | |
| SCHEMBL11635373 | 0.71 | CYP19A1 (0.48) | CYP11B1CYP11B2POLBCYP19A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4078071-A | FUNGICIDES, BACTERICIDES, ANTIPROTOZOA AGENTS | SYNTEX (U.S.A.) INC. (US) | 1978-03-07 | — | — | US | disclosed |