Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17005867 | 0.86 | ALDH1A1 (0.54) | ALDH1A1KDM4EPOLBALOX15HTT | |
| SCHEMBL31464036 | 0.85 | CYP2D6 (0.78) | ALDH1A1KDM4EALOX15HTTCYP2D6 | |
| SCHEMBL11629708 | 0.83 | ALDH1A1 (0.58) | ALDH1A1KDM4EALOX15HTTCYP2D6 | |
| SCHEMBL30573474 | 0.82 | CYP2C19 (0.67) | ALDH1A1KDM4EPOLBHTTKMT2A | |
| SCHEMBL27140798 | 0.81 | KDM4E (0.73) | ALDH1A1KDM4EALOX15HTTCYP2D6 | |
| SCHEMBL6991655 | 0.81 | KDM4E (0.65) | ALDH1A1KDM4EALOX15HTTCYP2D6 | |
| SCHEMBL31618631 | 0.81 | ALDH1A1 (0.75) | ALDH1A1KDM4EPOLBKMT2AMEN1 | |
| SCHEMBL20381978 | 0.79 | KMT2A (0.62) | ALDH1A1KDM4EALOX15HTTCYP2D6 | |
| SCHEMBL17028828 | 0.79 | ALDH1A1 (0.48) | ALDH1A1KDM4EPOLBALOX15HTT | |
| SCHEMBL21044159 | 0.79 | MEN1 (0.70) | ALDH1A1KDM4EALOX15HTTCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4092416-A | Benzopyrone derivatives exhibiting anti-allergic activity | BOEHRINGER MANNHEIM GMBH (DT) | 1978-05-30 | — | — | US | disclosed |