Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31464036 | 0.85 | CYP2D6 (0.78) | KDM4EALOX15ALDH1A1HTTKMT2A | |
| SCHEMBL27140798 | 0.81 | KDM4E (0.73) | KDM4EALOX15ALDH1A1HTTKMT2A | |
| SCHEMBL11633489 | 0.81 | ALDH1A1 (0.70) | KDM4EALOX15ALDH1A1HTTKMT2A | |
| SCHEMBL31708875 | 0.81 | KDM4E (0.61) | KDM4EALOX15ALDH1A1HTTKMT2A | |
| SCHEMBL21044159 | 0.79 | MEN1 (0.70) | KDM4EALOX15ALDH1A1HTTKMT2A | |
| SCHEMBL27882880 | 0.78 | KDM4E (0.60) | KDM4EALOX15ALDH1A1HTTKMT2A | |
| SCHEMBL30064669 | 0.78 | KDM4E (0.67) | KDM4EALOX15ALDH1A1HTTKMT2A | |
| SCHEMBL3602510 | 0.78 | FAAH (0.69) | KDM4EALOX15ALDH1A1KMT2AMEN1 | |
| SCHEMBL27615799 | 0.78 | MEN1 (0.64) | KDM4EALOX15ALDH1A1HTTKMT2A | |
| SCHEMBL12856249 | 0.78 | MEN1 (0.72) | KDM4EALOX15ALDH1A1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1332127-A2 | AMIDINO-UREA SEROTONIN RECEPTOR LIGANDS AND COMPOSITIONS, THEIR PHARMACEUTICAL USES, AND METHODS FOR THEIR SNYTHESIS | Warner-Lambert Company LLC (US) | 2003-08-06 | — | — | EP | disclosed |
| WO-2002036554-A2 | AMIDINO-UREA SEROTONIN RECEPTOR LIGANDS AND COMPOSITIONS, THEIR PHARMACEUTICAL USES, AND METHODS FOR THEIR SNYTHESIS | WARNER-LAMBERT COMPANY LLC (US) | 2002-05-10 | — | — | WO | disclosed |