Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11636893 | 0.86 | MAPT (0.33) | — | |
| SCHEMBL11637973 | 0.85 | THRB (0.35) | — | |
| SCHEMBL11637701 | 0.75 | — | — | |
| SCHEMBL1605453 | 0.68 | CNR2 (0.37) | HSD11B1EPHX2IRAK4 | |
| SCHEMBL11633752 | 0.68 | MAPT (0.32) | — | |
| SCHEMBL11636742 | 0.65 | MEN1 (0.33) | — | |
| SCHEMBL11637979 | 0.63 | — | — | |
| SCHEMBL11633724 | 0.61 | MAPT (0.32) | — | |
| SCHEMBL11637706 | 0.60 | — | — | |
| SCHEMBL11634708 | 0.59 | RAB9A (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4100170-A | ANTIHYPERTENSIVE AGENTS, MONOAMINE OXIDASE INHIBITORS | PENNWALT CORPORATION (US) | 1978-07-11 | — | — | US | disclosed |