Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11636893 | 0.77 | MAPT (0.33) | MAPT | |
| SCHEMBL11633600 | 0.71 | MEN1 (0.31) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL11634708 | 0.69 | RAB9A (0.35) | — | |
| SCHEMBL11633748 | 0.65 | HSD11B1 (0.34) | — | |
| SCHEMBL11637973 | 0.65 | THRB (0.35) | L3MBTL1ALDH1A1 | |
| SCHEMBL1605745 | 0.57 | ALDH1A1 (0.33) | KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL1605818 | 0.57 | LMNA (0.35) | L3MBTL1ALDH1A1 | |
| SCHEMBL60897 | 0.55 | GRIN2D (0.48) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL14503283 | 0.53 | EPHX2 (0.80) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL11635870 | 0.53 | GRIN2D (0.32) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4100170-A | ANTIHYPERTENSIVE AGENTS, MONOAMINE OXIDASE INHIBITORS | PENNWALT CORPORATION (US) | 1978-07-11 | — | — | US | disclosed |