Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.54 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.54 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.48 |
| ▸ | MAPT | P10636 | 9/20 | 0.48 |
| ▸ | MEN1 | O00255 | 8/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | RECQL | P46063 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | BLM | P54132 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | EP300 | Q09472 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11633825 | 1.00 | SIRT1 (0.54) | SIRT1SIRT5SIRT2ALDH1A1KMT2A | |
| SCHEMBL11640059 | 0.83 | TNFRSF1A (0.48) | SIRT1SIRT5SIRT2ALDH1A1KMT2A | |
| SCHEMBL14712995 | 0.76 | BCL2A1 (0.61) | SIRT1SIRT5SIRT2ALDH1A1KMT2A | |
| SCHEMBL14712869 | 0.76 | BCL2A1 (0.61) | SIRT1SIRT5SIRT2ALDH1A1KMT2A | |
| SCHEMBL14839892 | 0.75 | ALDH1A1 (0.53) | SIRT1SIRT5SIRT2ALDH1A1KMT2A | |
| SCHEMBL17460919 | 0.72 | MEN1 (0.58) | ALDH1A1KMT2AMAPTMEN1RECQL | |
| SCHEMBL10036062 | 0.71 | ALDH1A1 (0.55) | ALDH1A1KMT2AMAPTMEN1POLB | |
| SCHEMBL21419256 | 0.71 | ALDH1A1 (0.43) | ALDH1A1KMT2AMAPTMEN1POLB | |
| SCHEMBL3757006 | 0.71 | MAPT (0.71) | SIRT1SIRT5SIRT2ALDH1A1KMT2A | |
| SCHEMBL3756999 | 0.71 | MAPT (0.71) | SIRT1SIRT5SIRT2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4108667-A | Photographic compositions and elements containing benzo[a]quinolizinium methine dyes | EASTMAN KODAK COMPANY (US) | 1978-08-22 | — | — | US | disclosed |