Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.50 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.50 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.50 |
| ▸ | METAP1 | P53582 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14426635 | 0.82 | ALDH1A1 (0.48) | ALDH1A1SIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL13317579 | 0.80 | METAP1 (0.60) | ALDH1A1SIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL3572467 | 0.77 | GSK3B (0.52) | ALDH1A1TDP1LMNAGAASMN1; SMN2 | |
| SCHEMBL3572468 | 0.77 | GSK3B (0.52) | ALDH1A1TDP1LMNAGAASMN1; SMN2 | |
| SCHEMBL14822865 | 0.76 | MAPT (0.58) | ALDH1A1LMNASMN1; SMN2MAPTMAPK1 | |
| SCHEMBL3811532 | 0.76 | MAPT (0.58) | ALDH1A1LMNASMN1; SMN2MAPTMAPK1 | |
| SCHEMBL3811533 | 0.76 | MAPT (0.58) | ALDH1A1LMNASMN1; SMN2MAPTMAPK1 | |
| SCHEMBL11633829 | 0.75 | SIRT1 (0.54) | ALDH1A1SIRT2SIRT1SIRT5TDP1 | |
| SCHEMBL11633825 | 0.75 | SIRT1 (0.54) | ALDH1A1SIRT2SIRT1SIRT5TDP1 | |
| SCHEMBL16465058 | 0.74 | ALDH1A1 (0.60) | ALDH1A1TDP1RAB9ALMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130087682-A1 | PHOTOELECTRIC CONVERSION DEVICE, IMAGING DEVICE, AND METHOD FOR DRIVING PHOTOELECTRIC CONVERSION DEVICE | FUJIFILM CORPORATION (JP) | 2013-04-11 | — | — | US | disclosed |