Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5510059 | 0.86 | KMT2A (0.52) | KMT2AALDH1A1SMN1; SMN2BCL2L1MCL1 | |
| SCHEMBL5503771 | 0.86 | KMT2A (0.52) | KMT2AALDH1A1SMN1; SMN2BCL2L1MCL1 | |
| SCHEMBL11409462 | 0.84 | KMT2A (0.46) | KMT2AALDH1A1SMN1; SMN2BCL2L1MCL1 | |
| SCHEMBL11527071 | 0.83 | ALDH1A1 (0.52) | KMT2AALDH1A1SMN1; SMN2CNR2MEN1 | |
| SCHEMBL11525232 | 0.82 | ALDH1A1 (0.53) | KMT2AALDH1A1SMN1; SMN2CNR2MEN1 | |
| SCHEMBL11635788 | 0.80 | CNR2 (0.52) | KMT2AALDH1A1CNR2TDP1LMNA | |
| SCHEMBL11529122 | 0.79 | POLB (0.45) | KMT2AALDH1A1SMN1; SMN2POLBTDP1 | |
| SCHEMBL11633948 | 0.78 | CNR2 (0.50) | KMT2AALDH1A1CNR2MEN1TDP1 | |
| SCHEMBL11531125 | 0.77 | LMNA (0.64) | KMT2AALDH1A1SMN1; SMN2MEN1POLB | |
| SCHEMBL11595726 | 0.77 | F10 (0.46) | KMT2AALDH1A1SMN1; SMN2POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156735-A | SALIDIURETICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-05-29 | — | — | US | disclosed |
| US-4118501-A | SALIDIURETIC ACTIVITY | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-10-03 | — | — | US | disclosed |