Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 10/20 | 0.45 |
| ▸ | GAA | P10253 | 10/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL667827 | 0.79 | CA2 (0.67) | CA2CA5AMAPTGAAGLA | |
| SCHEMBL456513 | 0.77 | MAPT (0.67) | CA2CA5AMAPTGAAGLA | |
| SCHEMBL28916359 | 0.73 | CA2 (0.60) | CA2CA5AMAPTGAAGLA | |
| SCHEMBL7043304 | 0.70 | GAA (0.64) | CA2CA5AMAPTGAAGLA | |
| SCHEMBL6680813 | 0.70 | CA2 (0.56) | CA2CA5AMAPTGAAGLA | |
| SCHEMBL1520890 | 0.70 | GAA (0.61) | CA2CA5AMAPTGAAGLA | |
| SCHEMBL458638 | 0.70 | CA2 (0.56) | CA2CA5AMAPTGAAGLA | |
| SCHEMBL28049803 | 0.70 | CA2 (0.56) | CA2CA5AMAPTGAAGLA | |
| SCHEMBL163118 | 0.69 | ALDH1A1 (0.61) | CA2CA5AMAPTGAAGLA | |
| SCHEMBL11635936 | 0.67 | LMNA (0.46) | LMNAHTTTDP1CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4112120-A | P-BENZOQUINONEDI-IMIDES | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-09-05 | — | — | US | disclosed |