Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 2/20 | 0.36 |
| ▸ | CCND1 | P24385 | 2/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11634272 | 1.00 | RAB9A (0.41) | RAB9AKMT2ANPC1KDM4EGAA | |
| SCHEMBL11631868 | 0.85 | NPC1 (0.52) | RAB9AKMT2ANPC1KDM4EGAA | |
| SCHEMBL11631867 | 0.85 | NPC1 (0.52) | RAB9AKMT2ANPC1KDM4EGAA | |
| SCHEMBL11633301 | 0.82 | CHRNB2 (0.47) | RAB9AKMT2ANPC1KDM4EGAA | |
| SCHEMBL11633305 | 0.82 | CHRNB2 (0.47) | RAB9AKMT2ANPC1KDM4EGAA | |
| SCHEMBL16915478 | 0.81 | RAB9A (0.55) | RAB9AKMT2ANPC1KDM4EGAA | |
| SCHEMBL16915477 | 0.81 | RAB9A (0.55) | RAB9AKMT2ANPC1KDM4EGAA | |
| SCHEMBL16915450 | 0.75 | KMT2A (0.47) | RAB9AKMT2ANPC1KDM4EGAA | |
| SCHEMBL16915451 | 0.75 | KMT2A (0.47) | RAB9AKMT2ANPC1KDM4EGAA | |
| SCHEMBL11631981 | 0.73 | NFE2L2 (0.58) | NPC1ALDH1A1HPGDHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4130650-A | 1-METHYL- OR DIMETHYL-AMINOETHOXY, 2-PYRIDYLVINYL-BENZENE | BOEHRINGER INGELHEIM GMBH (DE) | 1978-12-19 | — | — | US | disclosed |