Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.41 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10623584 | 0.80 | SRD5A2 (0.40) | TP53SRD5A2MAPTRAB9ACA12 | |
| SCHEMBL472544 | 0.79 | MEN1 (0.45) | HSP90AA1MEN1KMT2ALMNAMAPT | |
| SCHEMBL1702198 | 0.79 | SRD5A2 (0.55) | SRD5A2KMT2ACA12CA9AKR1C3 | |
| SCHEMBL10800979 | 0.77 | ACHE (0.42) | TDP1MEN1KMT2ALMNAMAPT | |
| SCHEMBL11634000 | 0.77 | KDM4E (0.49) | TP53SRD5A2MEN1KMT2AMAPT | |
| SCHEMBL11632026 | 0.77 | ALDH1A1 (0.44) | SRD5A2MEN1KMT2AMAPTRAB9A | |
| SCHEMBL8086579 | 0.76 | MEN1 (0.45) | HSP90AA1MEN1KMT2ALMNAMAPT | |
| SCHEMBL3634185 | 0.76 | SRD5A2 (0.55) | SRD5A2KMT2AMAPTAKR1C3TTR | |
| SCHEMBL11011874 | 0.75 | TDP1 (0.47) | TDP1TP53SRD5A2MEN1KMT2A | |
| SCHEMBL11160025 | 0.75 | ACHE (0.46) | TDP1MEN1KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4103015-A | TRICYCLIC THIOXANTHONE-10,10-DIOXIDES | BURROUGHS WELLCOME CO. (US) | 1978-07-25 | — | — | US | disclosed |